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Hi, i`m Richard, a Veterinarian from the UK. Hopefully I can help today.
Does his skin look sore or irritated? Any flakes of skin apparent?
These guys can often pick up mites from their bedding causing skin signs such as this. I think a fungal infection is unlikely but I cannot fully rule it out. If he has skin mites, they can be effectively treated with skin drops containing ivermectin. The preparations are usually sold in pet stores and are suitable for birds and small rodents. It is best dosed every 2 weeks for 3 applications. In the UK these drops are marketed under the brand name Xeno, however this may be different in your country. Good pet stores should carry them and will be able to advise you of a suitable dose for him. The improtant thing is that it contains IVERMECTIN.
I`m still here. Cushings disease is a possibility, however it can be very difficult to treat in hamsters. If it is a mite problem (much more common than cushings disease) then if we can kil off the mites, the itching should improve and the fur should return.
Weight loss can just be an indicator that he hasn`t been feeling great. They can often also appear thinner as they lose hair, so it can be subjective. Have you noticed any signs of diarrhea or changes in his thirst?
are you having to fill his water bottle more frequently? It is usually the other way around, usually the bedding etc is more wet if they have a problem, which usually means more smells.
ok. I would recommend treating for mites initially. You should be seeing some improvement in an initial 2 weeks but I would recommend 3 doses in total 2 weeks apart, even if he does seem to be improving.
You are very welcome, hopefully he is feeling much more his normal self very soon!