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Urine Cytology Related Questions

Urine cytology is a method of testing that detects abnormal cells in urine. In many cases, urine cytology, in conjunction with other tests, is used to diagnose cancers of the urinary tract. While the most common use for this test is to diagnose bladder cancer, it also indicates various other kinds of cancers.

To learn more about urine cytology tests, take a look below at the questions that have been answered by the Experts.

Is a urine cytology test collected over three days a good test for detecting bladder cancer?

Urine cytology test results may not be 100% accurate all the time. Many people have false positives and false negative results. For this reason, a final diagnosis usually isn't made based on one test.

If a person's doctor suspects that they could have cancer, further testing is usually performed. Testing generally includes blood work, X-rays and, in some cases, a biopsy too.

Should a follow up urine cytology be taken if test results are “suspicious” for urothelial neoplasia?

Case details: Cystoscopy done a month later says normal. Woman has persistent asymptomatic hematuria.

Typically, a doctor may reschedule another urine cytology test if they are not content with the results. In most cases, urine cytology gives one specific results only if the patient has a high grade cancer. Many times, with a low grade cancer, the rate of false positives tend to be high. Therefore, if the urine cytology results appear suspicious, doctors usually recommend a second test.

What does it mean on a urine cytology report when it says that squamous epithelial cells are present and there are nuclear cytopathic changes?

When a urine cytology test shows the presence of squamous epithelial cells, it means that the test has been contaminated by skin located in the vulvar region. . However, the nuclear cytopathic changes may indicate HPV and usually requires a Pap smear by a gynecologist to check the health of the cervical area. If there is blood found in the urine, it could indicate a possible bladder tumor and may require a cystoscopy to view the inside of the bladder.

How does the sensitivity of FISH compare to Urine Cytology (UC) for low grade bladder cancer?

Generally, the FISH test may be more effective in detecting low grade bladder cancer as opposed to a urine cytology test. Fish has also been considered to be more sensitive to high grade cancers than cytology. However, the drawback with FISH is a higher rate of false positive results with both low and high grade cancers. Infection or bladder stones may also play a role in false positive and negative readings.

Many medical questions can arise when a person is asked to take a urine cytology test. In several cases, a false positive could also appear which may require additional tests. If you have any questions regarding urine cytology testing, ask an Expert right away. They can offer medical insights and suggestions for proper treatment plans based on the facts of your case.
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