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Non-Hodgkin’s Lymphoma Questions

What is Non-Hodgkin’s Lymphoma?

Cancer of the lymphatic system can be referred to as Non-Hodgkin’s lymphoma. The lymphatic system is part of the immune system and can be found throughout the body. When this condition is present, cells in the lymphatic system may not die normally or grow without control. There are many different types of lymphoma. Intermediate grade and high grade lymphomas can cause severe symptoms and grow quickly. Indolent or low grade lymphomas are nonaggressive which can have few symptoms and grow slowly. When someone is showing signs of Non-Hodgkin’s Lymphoma, questions can arise about the symptoms, treatments and possible cure. Read below for questions that have been answered by Experts.

What is the difference between Hodgkin’s disease and Non-Hodgkin’s Lymphoma?

Hodgkin’s disease is a group of cancers that are referred to as lymphomas. When Hodgkin’s disease is present in the lymph nodes in the neck it can first spread to the nodes located above the collarbone and into the chest. This condition can spread to other parts of the body and is treated with chemotherapy or radiation. A doctor can decide to use either a combination or one treatment methods. Although there are many different types of Non-Hodgkin’s Lymphoma, these all start in the cells of the lymphatic system. In the lymph nodes either B or T cells can become abnormal. Normally the lymphoma starts in the B cells.

What is the Non-Hodgkin’s Lymphoma Stage 3 prognosis?

Third stage Non-Hodgkin’s Lymphoma can be partially spread to extra-nodal organs, a site below and above the diaphragm and also affect two groups of lymph nodes. The grade or aggressiveness of the lymphoma can help determine the overall prognosis. Indolent Non-Hodgkin’s Lymphoma can be slowly progressive and may respond temporarily to treatment and may not be curable. Intermediate and high grade lymphomas may be curable with the use of combinations of chemotherapy. A number of prognostic factors help determine the long term survival or cure rates. The prognostic system that is used for Non-Hodgkin’s lymphoma is the International Prognostic Index or IPI. Five factors are used in this system, which include:
• Age
• Performance status
• Lactate dehydrogenase level
• Clinical stage
• Sites of extra-nodal disease

What are Non-Hodgkin’s Lymphoma treatments before a bone marrow transplant?

Treating transplant eligible Non-Hodgkin’s lymphoma, Ifosfamide, Carboplatin and Etoposide can be used. These medications are given in three treatments that are spaced at two weeks apart. For the best chance of survival, a doctor will often recommend a bone marrow transplant follows high dose chemotherapy. The chemotherapy can be used to destroy as many lymphoma cells as possible for the transplant is started. There could be a risk of the transplant being rejected or failing.

Why would the liver become grossly enlarged during treatments for Non-Hodgkin’s Lymphoma?

A grossly enlarged liver in Non-Hodgkin’s Lymphoma can represent the liver is involved in the disease process. Chemotherapy can positively affect the entire disease process. However, there can be some compromise to the liver functions because of the involvement. The chemotherapy medications can also adversely affect the liver functions. The effect on the liver can be caused by the medications being excreted by the liver.

The prognosis of this disease can be found by many different factors. Anytime someone is showing signs of Non-Hodgkin’s Lymphoma questions and concerns can arise. Questions about the treatments and reactions can be answered when asking Experts.
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