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Fluconazole Questions

What is fluconazole and what are its contraindications?

Fluconazole is used in prevention and treatment for fungal infections that are superficial and systemic as this is a triazole antifungal drug. Commonly this medication is sold under trade names such as Diflucan and Trican it begins in bulk form that presents as a white crystalline powder. It is often soluted in water or alcohol.

Individuals should not use fluconazole if they are hypersensitive to other medications that are azole or if they are pregnant. Other patients that should not use this drug if they are taking terfenadine, Selective serotonin re-uptake inhibitors (SSRIs), or using quinidine when fluconazole is given in high doses.

Concerns about this medication may arise for many individuals. Uncertainties about fluconazole side effects or effectiveness against illness can often lead to questions much like those answered below by Experts.

What are fluconazole side effects?

Clinical trials testing individuals taking fluconazole for a period longer than seven days has shown to create side effects in 1%-2% of individuals. These side effects included:
• Skin rash
• Nausea
• Headaches
• Diarrhea
• Vomiting
• Abdominal pain

Some rare side effects include hepatic (liver) reactions that range from mild elevations to hepatitis, cholestasis, and fulminant hepatic failure. Other rare fluconazole side effects include:
• Anaphylaxis
• Fever
• Malaise
Fatigue
• Seizures
• Dizziness
• Leukopenia
• Dry mouth
• Myalgia
• Tremor
• Vertigo
• Toxic epidermal necrolysis

Does fluconazole affect birth control?

Studies have shown that fluconazole may have a significant interaction with oral contraceptive birth control. When taken with birth control it may raise the estrogen levels. This is thought to compromise the oral contraceptive’s effectiveness against pregnancy. While using fluconazole treatment it is advised to use an additional form of birth control such as condoms until the next menstruation cycle to be safe in preventing pregnancy.

What is the recommended dosage for fluconazole nasal spray?

The triazole antifungal drug fluconazole is not available in a nasal spray. The correct dosage of the drug ranges from 100 milligrams (orally or intravenously) for typically fungal infections up to 400 milligrams for infections that are systemic candidiasis. Individuals may find treatment can last anywhere from three days up to two months depending on the type of fungal infection and severity. Generally the initial dose for individuals is 200 milligrams a day.

What can be used as treatment if prednisone and fluconazole for thrush is causing breathing issues (tightening of the throat) that worsen when sleeping?

Oral thrush is caused by candida albicans and stress, certain medications, or conditions can allow for this yeast to thrive and grow. Using a medication such as prednisone can cause thrush to grow due to aggravation.

Proper treatment would be to use an antifungal drug such as fluconazole. This can cure thrush but often 24 -48 hours is needed before the effects of the drug can be seen. If breathing issue become worse or are bothersome to where there is great discomfort with breathing then medical help should be sought immediately.

Would an irregular or fast heartbeat be caused by fluconazole or potassium supplements?

Irregular or fast heartbeat is known as a rare side effect of fluconazole but is also a side effect of low potassium levels. Fluconazole should be taken with caution if individuals already have an abnormal heart beat or heart disease as it has the potential to alter the way the heart itself beats. This can cause serious side effects or fainting episodes.

Having accurate fluconazole information can benefit individuals who have questions about this antifungal drug. Experts can help answer questions about alternatives to fluconazole treatment or what to do when faced with fluconazole complications. Get your questions answered by asking an Expert.
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