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Deramaxx for Dogs

Deramaxx, also known as Deracoxib, is a nonsteroidal anti-inflammatory medication (NSAID). This medication is commonly used to ease the symptoms of canine osteoarthritis. Your veterinarian may also prescribe Deramaxx for post-operative symptoms such as pain and swelling.

Benefits of deramaxx

Many veterinarians view Deramaxx as a safer option over other NSAIDs. This medication blocks the cox-2 enzyme while other NSAIDs block the cox-1 inhibitor enzyme. Blocking the cox-1 enzyme create health issues as it is needed for many of your dog’s bodily functions. The cox-2 enzyme promotes pain and inflammation.

Owners using Deramaxx have stated they see marked improvement within days of treatment. Results of the medication will depend on the severity of your dog’s condition. Joint mobility  is improved and lameness is g reduced. Some symptoms disappear completely which greatly improves your dog’s quality of life. The beef flavored chewable pill encourages most dogs  to swallow it rather than spit it out.

Side effects

Side effects vary from mild to severe for different dogs. In rare cases, death can occur. If you notice any of the following symptoms, stop the medication and contact your veterinarian for further instructions.

  • Change in behavior
  • Vomiting
  • Lack of appetite
  • Change in water intake
  • Change in urine
  • Change in stool appearance and consistency


Inform your vet of any health concerns or issues your dog has. Health issues such as pregnancy, liver disease, congestive heart failure, fluid retention, heart disease or high blood pressure may require an alternative treatment.

Drug interactions

Notify your vet of any prescription or over-the-counter (OTC) medications your dog is taking before using Deramaxx. Many OTC medications and supplements can interact with Deramaxx leading to further health issues.

While using Deramaxx, you should avoid all NSAIDS and Corticosteroids such as aspirin, prednisone, carprofen, and etodolac. Your veterinarian will look for possible drug interactions.


Before giving your dog Deramaxx, ask your veterinarian to explain dosing and administering. Understanding the correct dosage will help avoid overdosing or toxicity. The dogs weight determines the dosage. Your doctor may prescribe a lower dose if your dog has certain risk factors such as age or other diseases. Monitor your dog for the following symptoms.

  • Change in activity level
  • Aggression
  • Change in bowel movements (diarrhea, black stools or bloody stools)
  • Increased water intake
  • Change in urine
  • Skin irritation
  • Sudden weight loss
  • Stomach issues
  • Seizures

If any of these symptoms appear, your veterinarian should be notified immediately.

Deramaxx poisoning

Deramaxx is relatively safe when given properly but does pose certain risks. Deramaxx poisoning can occur if the dog has taken too large a dose or if an interaction with another medication occurs. While effectively reducing pain and inflammation, the NSAID can affect the prostaglandins. Prostaglandins initiate pain and swelling of the joints but also protect the dog’s stomach lining, support platelet formation, and ensure proper blood flow to the kidneys.

Certain dogs with the following pre–existing conditions have a higher risk of poisoning.

  • Renal disease
  • Cardiac disease
  • Pregnant or nursing dogs
  • Gastric ulcers
  • Hyperproteinemia
  • Dehydration
  • Hepatic disorders

Giving too large of a dose may cause serious illness or death. If your dog requires less than 12.5mg of Deramaxx, your veterinarian may tell you to break a 12mg tablet in half to get two 6mg doses. Adverse reactions resulting in improper dosing include

  • Stomach tenderness
  • Sudden weight gain
  • Water retention
  • Bloody or black stools
  • Blood in vomit
  • Fatigue
  • Skin sensitivity
  • Yellowing of the eyes
  • Bruising or bleeding

It is better to miss a dose rather than double up on Deramaxx. This medication is given once a day. If you give your dog a dose every morning and you remember at noon, you can still give the dose. However, if you remember the forgotten dose at 10 PM, skip that dose and return to the dosing schedule the following morning.

Treating Deramaxx poisoning

Poisoning symptoms are similar to an overdose. When these symptoms appear, it is important to seek medical attention as soon as possible. Your veterinarian must provide treatment for the poisoning. Treatments include gastric irrigation to remove the medication from the digestive system. Your dog will be sedated with general anesthesia for this procedure. IV fluids, pain medication, and additional supportive steps may be required. The dog will receive large amounts of fluids to prevent renal failure.

Full recovery from Deramaxx poisoning depends on the amount of damage done and how soon the poisoning is caught. Ensuring your dog is hydrated and comfortable is essential in recovery. You may notice your dog being unstable and confused after surgery. Grogginess is a typical reaction caused from the general anesthesia. Your dog may need help navigating for several hours.

Dogs affected by Deramaxx poisoning can expect numerous visits to the veterinary clinic for follow–up testing. Treatment can be expensive ranging from $250 - $2,500. The price of therapy will vary depending on location.

Homeopathic alternatives

Many people prefer to take the natural approach rather than pharmaceutical and some dogs may not be able to tolerate Deramaxx. There are a variety of natural approaches used to treat pain and inflammation for dogs. While homeopathic medicine is controversial, you may feel safer treating your dog’s pain naturally.

Zeel is a homeopathic blend that was used in a small study group of dogs. After eight weeks of taking Zeel, there was an improvement compared to the dogs who received a placebo.

Corydalis is a Chinese herb that has anti–inflammatory properties. As a natural analgesic, Corydalis controls inflammation and pain without harming your dog’s gastrointestinal tract.

Boswellia resin is extracted from the Boswellia tree native to South Africa, India, and the Middle East. The resin is used to make herbal compounds. It is an anti–inflammatory and can be used long-term without risking stomach damage.

California Poppy is used more for post-operative pain as it provides a mild sedative effect. This contains trace amounts of morphine and works as an analgesic.

 Arnica is an herbal liniment that is applied to your dog’s sore joints. Arnica provide relief when powerful NSAIDs and Tramadol fail to work. This liniment will provide fast relief that lasts for hours. However, Arnica is toxic if taken internally. Therefore, you should prevent your dog from licking the affected area.

Essential oils can be very effective in managing pain and inflammation. Combining capaiba, peppermint, and wintergreen essential oils can provide your dog with hot or cold relief. Many holistic veterinarians use essential oils due to the impressive results. Simply blend the oils and massage into the affected area.

As a dog owner, being informed about his medications will help you better understand how Deramaxx works. Knowing the benefits and risks of Deramaxx may offer information that you can apply during your dog’s treatment. If you are looking for more information on Deramaxx for dogs, ask an Expert.

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