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Who is he to you?
What are your ages?
Was he close to his uncle?
How long has it been?
Is he acting normal otherwise?
Sometimes it's difficult for people (especially men) to know how to express their grief. As long as you let him know that you are there for him anytime day or night then that's all he needs to know. Keep an eye on him if he seems to be acting erratic, or like he might do something to hurt himself, but in the meantime, be there for him but maintain a distance. If he doesn't want to be touched right now, give him that space until he's ready to be back in the world so to speak. He has looked upon you as his rock, so don't take his actions personal, it's just his was of trying to deal with his grief.
I welcome your thoughts, let me know if you want to talk more