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Answered in 1 minute by:
8/31/2017
Dr Mike, PharmD, Pharmacist
Category: Pharmacy
Satisfied Customers: 204
Experience: Doctor of Pharmacy, 20+ yrs experience, trained at the University of Iowa
VerifiedHello, DrMike at your assist...
I'm just looking at your question now.
diphenhydramine is the antihistamine (a specific type of antihistamine that does nothing for stomach issues, but it works well for sleep), and Nexium is a proton-pump inhibitor, so they're two different classes of medications. But, the important thing, is that there are no significant interactions between the two (or the melatonin).
Interactions are quite complicated. (See the above reference... Seldane and Benadryl are both antihistamines, but because one is processed a bit differently by the body, one could be fatal - depending on what other med/s you might combine it with).
Dr Mike, PharmD, Pharmacist
Category: Pharmacy
Satisfied Customers: 204
Experience: Doctor of Pharmacy, 20+ yrs experience, trained at the University of Iowa
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