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Drugdad, Pharmacist
Category: Pharmacy
Satisfied Customers: 1726
Experience:  I have a doctor of pharmacy degree with experience in both retail and hospital. I will be happy to share this knowledge with you
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Is it possible that prescriptions can vary from pharmacy to

Customer Question

Is it possible that prescriptions can vary from pharmacy to pharmacy? My daughter is taking Hydroco/acetamin for pain. She has to have a blood check to see if she is taking it.
She had to change pharmacy because of the new law. She never had a problem of the test showing positive with the first pharmacy. With the one she changed to, it is always negative. I know she is taking them because she would hurt too much. Also she has noticed that she has had more pain with the last pills.
Submitted: 1 year ago.
Category: Pharmacy
Expert:  Dr. Bridget replied 1 year ago.

Hi Gloria,

Thanks for your question! If I am interpreting your question correctly, Hydrocodone/Acetaminophen tablets may be from different manufacturers when obtained from different pharmacies, but the chemical formulation is the same and should not cause a drug screen to be negative. If you have the tablets and can give me a description (color and markings on them), I can check to be sure that what she is taking is actually Hydrocodone/Acetaminophen and not another medication packaged in the bottle in error. Another possibility is a false negative. This may occur for many reasons including taking a dose too low to be detectable or lab error (did the wrong test, mixed up results). If you think it is a false negative, let the prescribing physician know why and explain that she would like to be re-tested. If this is the first time something like this has happened to her, the prescriber should allow this.

Please let me know if you have any follow-up questions- I will be happy to respond. If the information I provided has helped you solve your problem, please let me know or provide a positive rating!


Dr. Bridget, PharmD,CGP