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Hello, JACustomer. I have been a Veterinary Nurse for over 15 years and would be happy to help you today. I'm reviewing your question right now.
It sounds like this mouse likely has a respiratory infection and could greatly benefit from a course of antibiotics. It would be best if she saw a veterinarian for treatment. At 18-24 months, she is at the life expectancy for a mouse, also, so this may indicate an underlying medical concern that could be terminal. Do you already have a vet that sees your pet mice?