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When Guinea Pigs have a head tilt lt can be from an ear infection spreading to the middle ear and inner ear. This causes a Vestibular issues, Vertigo. This type of infection can cause the head tilt aka torticollis. THis is know as “wry neck”. It also causes the loss of equilibrium and nausea. In this case, I suggest a Vet visit with a Guinea Pig Vet. If the Piggies is not eating and drinking we will have to force feed. This is a list of Guinea Pig Vets: http://www.guinealynx.info/vetlist.html
To force feed use Pedialyte and water 50/50 for fluids. For food you can grind the pellets into a fine power and mixing with the Pedialyte and water and make a slurry and syringe fed.
What you want to do is hold the Guinea pig and with the other hand syringe feed or if you have help. We have to keep food and fluids going in. Without food he can get a GI stasis and without fluids we are looking at dehydration. feed from the side of the mouth in small increments as not to aspirate the Guinea Pig. If you can get the Guinea pig into the Vet in the morning you can let it go with feeding tonight. If you feel the Guinea pig is in a critical situation, then a Vet in the ER can treat for you and give fluids and start medication.
Hope all will be ok , with the Piggie.