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Hi this is Dr Reupert. I'm sorry to hear Priscilla has anxiety. This is a very common problem in geriatric dogs. We call it night wandering and may be a form of dementia. Another possibility is tinnitus or hearing things that aren't there associated with hearing loss and ear nerve damage. I usually recommend trying to play a radio or television at night to see if this can make a difference. A night light sometimes helps. It is usually temporary, but a low dose of an anti anxiety medication such as valium or xanax can help given at bedtime until it passes.
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quetiapine does not appear to be safe for dogs, and I could not find very much on its use in dogs. Long term use was associated with cataracts.
xanax... 0.01 to 0.05 mg /kg
valium...0.05 to 0.1 mg/kg