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Hi. This is Dr. Hill. I am sorry that Gryphon is having seizures. The best thing to do is allow him to have the seizure and document how long he is actively seizing. If he has never had a seizure before, then he ideally should go to your local emergency clinic tonight. If he is known to have seizures, then as long as the active part of his seizure does not last beyond one minute and he has less than three seizures in a 24 hour period, then you are generally okay to wait until the morning to see your local veterinarian. Great danes are majestic animals. It is very hard to watch them have a seizure. I hope this helps. Please send me any additional questions. take care
How is Gryphon? I have a great dane named Griffin.