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Although the only person who can really make the decision to euthanize your pet is you, I think the biggest thing you can factor in is quality of life. If your pup is in pain that you cannot control or alleviate, if your pup no longer does any of the things she likes to do, then that is the point in time where you must consider that not forcing the animal to linger on is a kinder choice.I think that it comes down to is trying to put the dog's comfort above your own pain of loss. 12 is a very good age for a dog to reach so you have done very well by her getting her there.At some point you may find the websitehttp://www.petloss.com/ and the rainbow bridge story some comfort. Hardest thing in the world about pets is that no matter how long they live its really never long enough, but making this decision for your beloved pet is the ultimate act of kindness...to end their suffering in spite of the pain and hurt it will cause you to lose her.
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Although it sounds awful, and the coughing you're describing, doesn't likely hurt any more than it hurts you to cough when you have a cold or upper respiratory infection.