Dog

Get Your Dog Care Questions Answered by Experts

Ask an Expert,
Get an Answer ASAP!

Dog

Ello, i am in Paris, france My dog 1,7 years old has been

Customer Question
ello, i am in Paris...
ello, i am in Paris , france
My dog 1,7 years old has been diagnosded by a Cryptoccocus on the 30th September (she had some 2 seizure on the same day before the verdict).
She has started the treatement with Fluconazole , at first 150 Mg (milligrams) per day, and now 200 Mg / day
Her type of Cryptococcus concerns probably her brain ,as she had an ulcere above the left eye, and she had the front bone destroyed (they discovered it when they extracted the cells to send them to the lab).
So from 30th September she has had 7 days of Treatement, but around the day 3 or 4 , her mobility went down, and now she can't move. when i help her to stand up, she is still alert and recognizes me, licks my hand, etc.. but she can't move since Saturday 3rd October. On the other hand she is week but still conscious and have good periods. At the moment she is at the vet clinic since Saturday for intensive care more or less. I can visit her several times a day.
Cryptococcus is extremly rare in france
Submitted: 2 years ago.Category: Dog
Show More
Show Less
Ask Your Own Dog Question
Answered in 18 minutes by:
10/6/2015
Dog Specialist: Dr. Michael Salkin, Veterinarian replied 2 years ago
Dr. Michael Salkin
Dr. Michael Salkin, Veterinarian
Category: Dog
Satisfied Customers: 31,762
Experience: University of California at Davis graduate veterinarian with 45 years of experience
Verified

I'm sorry to hear of this with Brystole. You're correct - cryptococcosis is more common in cats but does occur in dogs who are more likely to be systemically ill and always have a guarded prognosis for recovery. The treatment of choice is, indeed, fluconazole because it crosses the blood-brain barrier but it's important to recognize that central nervous system infections as you've described in Brystole can be difficult to clear. Dogs such as she may also need surgical removal of infected tissue (cytoreduction of large granulomatous lesions). I regret to tell you that her paresis (weakness)/paralysis at this time is a very negative prognosticator for her eventual recovery. Please respond with further questions or concerns if you wish.

Ask Your Own Dog Question
Customer reply replied 2 years ago
if the cryptococcus has crossed the blood brain barrier, is it too late? Let's say the fluconazole is starting to act, is it possible she starts to get better and walks again ?
Tomorrow they are planning to make a scanner to her with a very light anesthesia, and she is planned to be "awake".
I am really worry if they can save my dog or if it's too late. She looks okay more or less when i see her and speak to her but about this mobility problem i am worried
Customer reply replied 2 years ago
i mean let's say she survives 5 or 10 more days and some signs that she gets better arrise , is it possible she walks again ?
Dog Specialist: Dr. Michael Salkin, Veterinarian replied 2 years ago

It's not necessarily too late but treatment would necessarily be quite protracted and the prognosis for functional recovery must remain quite guarded. Yes, if damage to her brain isn't permanent she can recover the ability to walk. It's difficult to predict how long that might take, however. The brain scan will tell you how involved her brain is in this infection. If multiple granulomas are found, Brystole won't be able to recover. If granulomas can't be seen in the scan, she has a chance!

Ask Your Own Dog Question
Customer reply replied 2 years ago
ok i will keep you updated with Tomorrow's scanner, in any case. i am quite afraid for her now.
Last thing for today, and i don't disturb you , let's say that no granulomas are found , then is it wiser to keep her some more days at the clinic, or is it fine to take her back with me. I ask this because it's starting to be quite costly (100 euros per day to keep her there, + blood test that i have to add ,etc.. ) ?
Dog Specialist: Dr. Michael Salkin, Veterinarian replied 2 years ago

I understand how costly this can become and there's no way to know how long treating her would be necessary. The husbandry necessary to care for these dogs can be lengthy and intensive and so home care - while possible - must be thought through carefully by you. Paralyzed dogs often require 24 hour care.

Ask Your Own Dog Question
Customer reply replied 2 years ago
Thks a lot doctor, i will keep you updated tomorrow about Brystol's health
Dog Specialist: Dr. Michael Salkin, Veterinarian replied 2 years ago

I appreciate it. I'll watch for your next post.

Ask Your Own Dog Question
Customer reply replied 2 years ago
Hello again, Scanner said that the crypto has passed the encephale ... Is there any chance left?
Dog Specialist: Dr. Michael Salkin, Veterinarian replied 2 years ago

I'm sorry to hear of this. Unless you've prepared for months of intensive care and considerable expense, euthanasia is a reasonable option for Brystole. What have her vets told you now that she's been scanned?

Ask Your Own Dog Question
Customer reply replied 2 years ago
The vets said that as it's the 7th day of anti-fungus, and maybe it's worth to try a few days more in order to see if the anti-fungus works or not because it's not yet at its pic of action (normally it's 10 to 15 days that it takes to start to show some signs of actions).
When we took her from the Scanner place, back to the veterinary in the afternoon, at some point she started to shout very loud while travelling her from the car back to the clinic. The vet said it's due to post-anesthesia...
I join you some photos of the scanner
I don't know what to do, if to try few more days or to euthanasian her
IMG_8718.JPGIMG_8718.JPGIMG_8719.JPGIMG_8719.JPGIMG_8720.JPGIMG_8720.JPGIMG_8726.JPGIMG_8726.JPGIMG_8721.JPGIMG_8721.JPGIMG_8722.JPGIMG_8722.JPGIMG_8723.JPGIMG_8723.JPGIMG_8724.JPGIMG_8724.JPGIMG_8725.JPGIMG_8725.JPG
Dog Specialist: Dr. Michael Salkin, Veterinarian replied 2 years ago

Thank you for the images. I'm not qualified to interpret these scans but even I can see the extensive bony destruction caused by the fungus. If the fungus has, indeed, invaded her brain, euthanasia might well be a kindness. I can't expect your being able to care for a paralyzed patient for the extended time necessary for a positive response to therapy much less cure. Treatment typically is given for months and will be quite expensive. I understand that you have a very difficult decision to make.

Ask Your Own Dog Question
Customer reply replied 2 years ago
i will think and will keep you updated.
Dog Specialist: Dr. Michael Salkin, Veterinarian replied 2 years ago

Thank you. I'll watch for your next post.

Ask Your Own Dog Question
Customer reply replied 2 years ago
Hello Doctor Salkin ,
Today I went to veterinary, and a bit he finds her mind slightly deteriorated since tuesday as she didn't react by clicking the eye when he did put a strong light near her left eye. Myself i looked at her, and i had the feeling she was the same than the previous days. She a bit reacted to my presence but as usual not much. Her Ears stood up but she had no energie to turn her head, but when i took her head she started to lick a bit my end.
On the other hand, it seems that the ulceria/oedeme lost 30% of his mass, and her left eye was a bit "more normal " than yesterday. So maybe anti-fungus starts acting!?
With the vet, we gave ourselves between 2 and 4 days where she will stay at the clinic and we will closely watch the evolution. If it's negative, then probably i will have to let her go, while if it's stable or a bit better, it will then be possible to bring her home and continue anti-fungus treatement from home.
Also I said him no blood test until extremly necessary, because all teh time it's between 200 to 300 USD for 17 Electrolytes, which is not nothing at the end ... On this he agreed.
I have also gotten the CD with the scanner, i will try to send you some of the pics (that are much more precise than the photos I sent you yesteday) .
Dog Specialist: Dr. Michael Salkin, Veterinarian replied 2 years ago

Thank you for the update. That all sounds reasonable to me. It's too early to see a meaningful response to that drug. Because of its long half-life, fluconazole doesn't reach steady state plasma levels for 6-14 days after beginning therapy. Depending upon response the dosage may be increased for refractory cases. Treatment will be required for months and generally should continue for 1-3 months after resolution of clinical signs.

Ask Your Own Dog Question
Customer reply replied 2 years ago
Hello !
I went to see brystole today afternoon too (so it's my second time today), she is like in the morning and other days , but her temperature is a bit down today. Normally in france by celsius, for a dog it should be between 38,2 and 38,6 , my dog had 36,8 in the morning (around 10,30) 36,4 in the afternoon (around 13,30) and later in the afternoon (at 16;30 paris time) she had 36,1°.
I came , gave a bit some food, she licked my fingers and took my food, then i stayeed a bit with her and let her sleep. But i don't know , to me she looked like the other days , not better not worse, only this temperature things a bit worries me. They putted a bit some covers on her
Dog Specialist: Dr. Michael Salkin, Veterinarian replied 2 years ago

Thank you for the update. Normal body temperature ranges between 38 and 39.2C. 36+C is worrisome and might indicate her brain unable to regulate her body temperature efficiently, drug toxicity, or a failing patient. You're correct to be worried.

Ask Your Own Dog Question
Ask Dr. Michael Salkin Your Own Question
Dr. Michael Salkin
Dr. Michael Salkin
Dr. Michael Salkin, Veterinarian
Category: Dog
Satisfied Customers: 31,762
31,762 Satisfied Customers
Experience: University of California at Davis graduate veterinarian with 45 years of experience

Dr. Michael Salkin is online now

A new question is answered every 9 seconds

How JustAnswer works:

  • Ask an ExpertExperts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional AnswerVia email, text message, or notification as you wait on our site. Ask follow up questions if you need to.
  • 100% Satisfaction GuaranteeRate the answer you receive.

JustAnswer in the News:

Ask-a-doc Web sites: If you've got a quick question, you can try to get an answer from sites that say they have various specialists on hand to give quick answers... Justanswer.com.
JustAnswer.com...has seen a spike since October in legal questions from readers about layoffs, unemployment and severance.
Web sites like justanswer.com/legal
...leave nothing to chance.
Traffic on JustAnswer rose 14 percent...and had nearly 400,000 page views in 30 days...inquiries related to stress, high blood pressure, drinking and heart pain jumped 33 percent.
Tory Johnson, GMA Workplace Contributor, discusses work-from-home jobs, such as JustAnswer in which verified Experts answer people’s questions.
I will tell you that...the things you have to go through to be an Expert are quite rigorous.

What Customers are Saying:

You are a light at the end of scary tunnel when $ are tight, but people need professional help to turn to for help with their dear pets!

LinhCharleston, WV

$1,000 spent at his vet, and I finally get the correct diagnosis from Nancy Holmes for $15

CarolCedar Hill, MO

I think this is the greatest web site in the world. Thanks to all!

JudyNew Haven, CT

I have referred several friends to your web site. I'm impressed with how easy it is to use your site, the Experts available and the quickness of answers.

NinaUSA

I am completely pleased with the quick response that I received in our time of need for our dog, Jasmine. I couldn't believe how quick the response was and I thank you. It's good to know you're there!!

Jasmine's MomUSA

Please let everyone involved with your site know that your Expert, Dr. Lucy, has saved my dog's life. I will recommend your site to all my pet loving friends. Thank you again for simply being there!

Sonya GEasley, SC

Last night my Expert spent close to 3 hours working with me on my dog's illness. Thank you so much for this opportunity to share in her care and knowledge!

Cathie MPompano Beach, FL

< Previous | Next >

Meet the Experts:

Dr. Gary

Dr. Gary

Dog Veterinarian

3,033 satisfied customers

DVM, Emergency Veterinarian; BS (Physiology) Michigan State Univ

Joan

Joan

Vet Tech

5,320 satisfied customers

Vet Tech for over 35+ years working w/Dogs/Rescues

Candy

Candy

Veterinary Technician

7,973 satisfied customers

Practicing Veterinary Technician for 26 years.Former Veterinary Practice Owner, Technician Trainer

Dr Scott Nimmo

Dr Scott Nimmo

Small Animal Veterinarian.

5,120 satisfied customers

BVMS, MRCVS. { Glasgow UK }

Dr. Andy

Dr. Andy

Medical Director

4,898 satisfied customers

UC Davis Graduate, Interests: Dermatology, Internal Medicine, Pain Management

Theresa

Theresa

A Voice for Your Pet

4,705 satisfied customers

19+ years experience in small animal medicine

Dr. Drew

Dr. Drew

Veterinarian

3,292 satisfied customers

Small Animal Medicine and Surgery

< Previous | Next >

Related Dog Questions
He got one of my Actos/metformin tablets and about 1/8 of it
He got one of my Actos/metformin tablets and about 1/8 of it is gone before I realized he had it. He is a 25lb mini- Aussie … read more
Dr Scott Nimmo
Dr Scott Nimmo
Small Animal Veterinarian.
5,120 satisfied customers
My dog just ate that was left out in my son's room... what
My dog just ate brownies that was left out in my son's room... what should I do? … read more
Dr Scott Nimmo
Dr Scott Nimmo
Small Animal Veterinarian.
5,120 satisfied customers
My dog has kennel cough and has been receiving antibiotics
My dog has kennel cough and has been receiving antibiotics for the last several days. While the cough is improving, he still has periodic coughing. Are there any foods that he should avoid? … read more
Dr. Deb
Dr. Deb
Associate Veterinarian
Doctoral Degree
564 satisfied customers
Just adopted from county shelter 10 days ago. She is 45 lb
Just adopted from county shelter 10 days ago. She is 45 lb Staffordshire mix. She was spayed, received 4-1 in vaccine, borderless & rearguard. Negative for heartworm,tick fever, Lyme disease & anaplas… read more
PitRottMommy
PitRottMommy
Veterinary Nurse
Associate Degree
9,162 satisfied customers
My approximately 6 week pregnant Shih Tzu has been panting
My approximately 6 week pregnant Shih Tzu has been panting heavily all evening. She has sparely touched her food but will eat treats. … read more
Jane Lefler
Jane Lefler
Dog Behaviorist/Trainer/Breeder/Health
3.75 GPA 36cr. Multiple Tech traini
0 satisfied customers
Dog is coughing frequently and the coughing is leading to
Dog is coughing frequently and the coughing is leading to frequent coughing up mucus (or more). It seems like kennel cough, plus some gagging due to the phlegm, etc. The vet wants to do an antibacteri… read more
PitRottMommy
PitRottMommy
Veterinary Nurse
Associate Degree
9,162 satisfied customers
Bright Bloody diarrhea. almost four. German Shepherd and on
German Shepherd and on a raw food diet that includes chicken and beef… read more
PitRottMommy
PitRottMommy
Veterinary Nurse
Associate Degree
9,162 satisfied customers
I have a 70lbs 5 year old Golden Retriever who had ECLS
i have a 70lbs 5 year old Golden Retriever who had ECLS surgery 3.5months ago. Since about the first week, she has had this popping noise coming from her leg. Took her to her surgeon, said it was air … read more
divealot1
divealot1
DVM
7 satisfied customers
He's a 6 month old husky and his pupils are dilated, he's
He's a 6 month old husky and his pupils are dilated, he's lethargic, can't seem to walk straight and the white of his eyes is slightly red, and he urinated when he was laying down … read more
Dr. Michael Salkin
Dr. Michael Salkin
Veterinarian
31,762 satisfied customers
My dog had a little blood on normally shaped stool. He's a
My dog had a little blood on normally shaped stool. He's a 12 year old neutered lab. They gave him a butorphanol injection at 4:30 pm to do abdominal xrays. His blood work was fine as were his X-rays.… read more
Dr. Michael Salkin
Dr. Michael Salkin
Veterinarian
31,762 satisfied customers
I have a 2 y/o female Dachshund named Minnie. About 3 weeks
I have a 2 y/o female Dachshund named Minnie. About 3 weeks ago I noticed a hairless area just below her left eye. At the time I first noticed the area it appeared flat. It seems as though it has beco… read more
PitRottMommy
PitRottMommy
Veterinary Nurse
Associate Degree
9,162 satisfied customers
My dog vomited this evening. Then did again 3 more times.
My dog vomited this evening. Then did again 3 more times. The last time there was only a little bit of liquid because his stomach was empty. He keeps licking his lips and I can hear gurgling in his be… read more
PitRottMommy
PitRottMommy
Veterinary Nurse
Associate Degree
9,162 satisfied customers
It might be vestibular disease. She has the symptoms. The
It might be vestibular disease. She has the symptoms. The problem is I'm snowed in and can't get to the vet. What can I do for her until I can? … read more
DakotaSouthFive
DakotaSouthFive
Independent Contractor
High School or GED
12 satisfied customers
We have a German Pinscher who had 9 puppies 19 days ago. We
We have a German Pinscher who had 9 puppies 19 days ago. We have a surrogate mother for a couple of the puppies who were very small. The mother is overloaded with this large litter and we have been tr… read more
PitRottMommy
PitRottMommy
Veterinary Nurse
Associate Degree
9,162 satisfied customers
My Rottweiler and husky mix puppy ate about 5 grapes
Hello, my Rottweiler and husky mix puppy ate about 5 grapes yesterday … read more
Dr. Michael Salkin
Dr. Michael Salkin
Veterinarian
31,762 satisfied customers
For last 24 hrs he's been screaming off and on that his
For last 24 hrs he's been screaming off and on that his belly hurts … read more
PitRottMommy
PitRottMommy
Veterinary Nurse
Associate Degree
9,162 satisfied customers
My dog ate a sock and is starting to show signs she doesn't
My dog ate a sock and is starting to show signs she doesn't feel well. This happened two days ago … read more
DakotaSouthFive
DakotaSouthFive
Independent Contractor
High School or GED
12 satisfied customers
Trying to vomit but nothing comes out. Chewing on tail,
Trying to vomit but nothing comes out. Chewing on tail, walking around … read more
PitRottMommy
PitRottMommy
Veterinary Nurse
Associate Degree
9,162 satisfied customers
Disclaimer: Information in questions, answers, and other posts on this site ("Posts") comes from individual users, not JustAnswer; JustAnswer is not responsible for Posts. Posts are for general information, are not intended to substitute for informed professional advice (medical, legal, veterinary, financial, etc.), or to establish a professional-client relationship. The site and services are provided "as is" with no warranty or representations by JustAnswer regarding the qualifications of Experts. To see what credentials have been verified by a third-party service, please click on the "Verified" symbol in some Experts' profiles. JustAnswer is not intended or designed for EMERGENCY questions which should be directed immediately by telephone or in-person to qualified professionals.

Disclaimer: Information in questions, answers, and other posts on this site ("Posts") comes from individual users, not JustAnswer; JustAnswer is not responsible for Posts. Posts are for general information, are not intended to substitute for informed professional advice (medical, legal, veterinary, financial, etc.), or to establish a professional-client relationship. The site and services are provided "as is" with no warranty or representations by JustAnswer regarding the qualifications of Experts. To see what credentials have been verified by a third-party service, please click on the "Verified" symbol in some Experts' profiles. JustAnswer is not intended or designed for EMERGENCY questions which should be directed immediately by telephone or in-person to qualified professionals.

Show MoreShow Less

Ask Your Question

x