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Dr.Fiona, Dog Veterinarian
Category: Dog
Satisfied Customers: 6273
Experience:  16 years experience as a companion animal veterinarian in British Columbia, California and Ontario
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Side effects of Noroclav antibiotic tablets on dogs

Resolved Question:

What side effects could the antibiotic tablets Noroclav Palatable 250mg cause? My Cocker Spaniel has been on them for 1 week and now he is pretty poor on health. The vet says they think he has an abnormal kidney; he is in a lot of pain and very lethargic. His blood test was okay. They have now got him on marbocyl p tabs 40mg.

Submitted: 9 years ago.
Category: Dog
Expert:  Dr.Fiona replied 9 years ago.

Welcome to Just Answer! What makes your vet think your dog has an abnormal kidney? Did the vet feel it on physical exam, or see it on an x-ray, or an ultrasound?

Does he have a fever?

When was he last seen by your vet?

Is he now on BOTH the Noroclav and the Morbocyl, or just one?

Is he eating and drinking normally?

Any vomiting or diarrhea?

Was a urine test done?

Customer: replied 9 years ago.

His temperature was high but it is ok now.

They said the kidney looked abnormal from the scan what they done.

Actually we had to take him this morning.

No just the morbocyl and painkillers which we were given this morning.

No he will not drink just from my fingers, he is eating a little bit I have him on light food such as chicken fish pasta and rice.

No vomiting but he had a little diarrhea on Saturday morning, he has only cleaned himself once since then.

Yes I had taken a urine sample last Tuesday of which he had an infection also he has got quite a lot puss coming from his penis this is also enlarged.

He has improved slightly over the weekend but he is still in pain, the Vet says it could be his prostrate as he is still tender in that area.

Expert:  Dr.Fiona replied 9 years ago.

So, your dog has an enlarged and painful prostate and is one marbocyl and painkillers? Also, one kidney looked abnormal from the scan done. He is not drinking or eating much.

The side effects of Noroclav antibiotic can be loss of appetite, diarrhea, and sometimes vomiting. Most dogs will not have these side effects but some will. In North America, this antibiotic combination is called Clavamox. Here is more about it:

With dogs with an enlarged prostate, there are a number of things that could be causing that. Some of these are BPH (benign prostatic hyperplasia), prostatitis, prostatic tumors, or prostatic abscesses. Benign prostatic hyperplasia is the most common prostatic disorder in the dog.

BPH is an enlargement of the prostate that is not caused by cancer, inflammation or infection. It is just caused by the effects of testosterone.

Prostatitis is an inflammation of the prostate and can be caused by infection. In order to diagnose prostatitis, I generally do a rectal to feel if the prostate is enlarged, and I do a prostatic wash. This involves placing a catheter in the urethra (up the penis), slowly injecting a small amount of warmed saline in while holding the tip of the catheter in the area of the prostate, and simultaneously massaging the prostate (from the rectum). What happens is that you then get a sample of the fluid from the prostate itself. This is a great way to detect low-grade infections of the prostate. I would have sent the fluid off for analysis and culture and sensitivity testing to know what the best antibiotic is to treat for this.

Here's more on prostate problems:

I'm unclear on whether your dog has had any diagnostic tests to determine if this is BPH or prostatitis, or a tumor or an abscess. Often, an ultrasound is recommended to be able to visualize the prostate better. This allows the vet to see if there is a tumor, abscess or other abnormality in there. A sample of the prostate might be taken using a needle.

Saw palmetto and nettle root have been used in humans to treat BPH. Studies in dogs have shown that it is not effective in them (though apparently it is in ferrets for some reason!). Instead, a more useful drug in dogs is Proscar (finasteride) which can reduce the size of the prostate.

Key Drugs, Dosages and Indications

Key Drug

Drug Class

Dose Range





LHRH agonist

Used to slow cancer growth in men


LHRH agonist

Used to slow cancer growth in men


LHRH agonist

Used to slow cancer growth in men

Proscar (finasteride)

4-aza-steroid inhibitor of 5-alpha reductase




Prostatic hyperplasia regression


(megestrol acetate)

5-alpha reductase inhibitor

0.25 mg/lb/day



Prostatic hyperplasia regression



Gram pos. and neg. prostatic infections

*Enrofloxacin (Baytril)


Chronic prostatic infections





Chronic prostatic infections (esp. effective against Pseudomonas spp.)

Orbifloxacin (Orbax)


Chronic prostatic infections

Difloxacin (Dicural)


Chronic prostatic infections



Reduce prostate cancer in men over 60

Saw palmetto

5-alpha reductase inhibitor

Reduce prostate hyperplasia

* Drug of choice for chronic bacterial prostatitis in dogs.

The more your boy drinks, the better it is going to be for his kidneys and his bladder as this will help to flush them out. There are a number of things you can do to increase water consumption.

- You can mix a bit of food in with water to make a soup - that way he may be enticed to drink more.

I suggest opening a can of tuna *in water* and offering the liquid diluted with water 50:50.

Any clear fluids are fine to give - such as apple juice, Gatorade, pedialyte. Dilute all of them 50:50 with water.

You could try Lactose Free milk (Lactaid is the Canadian brand).

Offer some canned dog food, and mix it with water to make gravy to pour over his dry food

Other things you can do to encourage a dog to drink are:

- offer water from a very wide flat bowl

- If he likes dripping water, leave a tap dripping for him.

- Offer bottled water and see if he prefers it.

- Offer chicken broth or beef broth, diluted 50:50

- See if he likes water with an ice cube in it.

- See if he likes it out of a cup or pasta bowl.

- You could try getting some human baby food in meat flavors (check that there are no onions or garlic in the ingredients) and mix that with warm water and offer that as a "soup" for her to drink. Beech Nut makes a line of baby food that has nothing but meat (beef, chicken, turkey or veal) in it. Here's a link:

If you cannot find this, you could find another meat baby food - just read the label carefully to be sure there are no onions, onion powder, garlic, or garlic powder in it.

Cook a chicken breast and put it in the blender with enough water to turn it into baby-food consistency. Make it into a soup.

Many dogs LOVE water from a water fountain like those shown here:

Hopefully, these ideas will help you to get some fluids into your dog so his urine is more dilute!

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