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Terri, Feline Healthcare Expert
Category: Cat
Satisfied Customers: 32666
Experience:  Expert in feline health and behavior. 20 years experience with cats.
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I gave my cat mirtazipine because she wasn't eating.. the

Customer Question

I gave my cat mirtazipine because she wasn't eating.. the vet told it it should help and now she is drooling like crazy, peed and pooped all over which isn't normal for her, she's isolating herself and still not eating.. it's been about 1 hour 30 mom since given to her.. is this normal and when will this wear off?? My cat is howling also if I try to move her.. so unlike her
Submitted: 3 months ago.
Category: Cat
Expert:  Terri replied 3 months ago.

Hello, My name is Terri.
It is my pleasure to assist you today!
I am reviewing your question right now and will reply in a few minutes.

Expert:  Terri replied 3 months ago.

Hi Beckie,

How long has she not been eating?

What food was she eating before she stopped?

Any other symtoms besides howlng?

Is she elwiminating normally?

Customer: replied 3 months ago.
She seems to not have too much control of bladder and bowel. She ate a tiny bit yesterday (as in a couple pebbles. ) and not much Saturday, she got a depo shot Saturday so that's why the Dr thought she wasn't eating and said it was ok to give her the mirtazipine. She eats Purina dry and friskies wet food.
Customer: replied 3 months ago.
She's howling, drooling and foaming, acting isolated, and peeing / pooping
Expert:  Terri replied 3 months ago.

Thanks so much for your very helpful reply.

Please give me a few minutes to type detailed answer.

Expert:  Terri replied 3 months ago.

Dear Beckie,

It sounds like she is very nauseated and the feeling is upsetting her.

Forget about mirtzapine, it is making her worse.

Instead get a few jars of chicken or turkey baby food with no onion powder.

First Give her one quarter of a ten mg pepcid a/c (famotidine). I usually add it to a tablespoon of baby food chicken with no onion or garlic.

Most cats will eat baby food and it is very mind for the GI tract.

Elevate her dishes:

She can have 2 drops of simethicone (gasX ) every 6 hours.

Remove all dry food and any wet with chunks, pieces or shreds.

Feed only smooth pate canned food or baby food.

If she gets dehydrated give her tuna water drained from the can.

Please let me know how she is doing .

Please be so kind as to rate my answer with positive feedback; that is the only way I receive credit for my assistance. Thank you very much!

Providing a positive rating will not end our conversation, should you need me for any follow-up. Simply click 'Reply' for clarification or additional information, if needed, at no additional charge.

Kind regards,


Customer: replied 3 months ago.
Okay but are all of these symptoms normal? And when will they start to wear off? I'm more concerned with the way she is acting right now and the symptoms the mirtazipine gave her
Expert:  Terri replied 3 months ago.

The symptoms indicate a severe GI upset and possibly a painful issue.

Did she have a fever at the vets?

Were any labs done? If so can you post them so I can evaluate her condition?

Customer: replied 3 months ago.
No labs no fever.. is this normal though and will they go away? Is this due to the mirtazipine? She wasn't like this before.. you're not really answering my questions
Expert:  Terri replied 3 months ago.

Many cats drool and have a hissy fit when given medication. That is why I always add it to palatable baby food.

The mirtzapine did not agree with her so don't give it again. This is definitely an adverse reaction to that drug

Customer: replied 3 months ago.
When will these symptoms go away
Expert:  Terri replied 3 months ago.

The pepcid should settle her stomach and negate the effects within a half hour of taking it.

Expert:  Terri replied 3 months ago.

Give it now (in baby food) and write back to let me know how she is

Expert:  Terri replied 3 months ago.

For what was she given depo medrol?

Customer: replied 3 months ago.
She was losing fur on her back legs and they thought it was allergies. She acted completely normal after except not eating so they said to give her this.
Expert:  Terri replied 3 months ago.

I see, she has feline alopecia. Do you ever see her over grooming those areas or did the fur just fall out by itself?

How long does she have that?

What is her current regular food?

can you post a picture?

Expert:  Terri replied 3 months ago.

Did you give her pepcid?

Is she any better?