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Hello. I am sorry to hear your girl is having some trouble. My name is ***** ***** I would be happy to help.
When did she last pass stool?
If she is a long haired kitty can you check and make sure there is no hair matted around her bottom?
Are you sure she is straining you pass stool. I ask because often when a cat has a urinary tract infection they will go in and out of the box, be painful and many times this is mistaken for constipation.
Any history of constipation?