Hello from JustAnswer. This is Dr. Love.
Yes, although it is usually not a reason to not use the drug.
For short term use of standard doses, there is very little effect on bone loss. However, with excessive use or with long term use, it is possible that it may contribute to bone loss. The amount of bone loss from Symbicort is usually not great, but in someone that is at higher risk because of other reasons for bone loss, the amount of bone loss from Symbicort may be enough that it may be an issue when added to the bone loss from other factors.
It is recommended that someone at risk for bone loss should be closely monitored if the Symbicort is needed for long term use.
However, even in the worst case of bone loss from Symbicort, the magnitude of bone loss is minor compared to the amount of bone loss from systemic steroids. The horror stories of steroid induced bone loss occurs with systemic use of steroids.
In addition, in people that have significant lung disease and several risk factors for bone loss, it is frequently still determined that the use of Symbicort to help breathing worth the risk of bone loss. If the lung disease can be controlled without steroids, that is fine, but if not, breathing is generally more important than avoiding medicines that may cause bone loss.
If I can provide any additional information, please let me know.