Oncology Questions? Ask an Oncologist for Answers ASAP
This is Dr. David
it sounds like the stem cell transplant didn't get rid of all of the lymphoma out of your system.
you have options for clinical trial research protocols
you can also get second line chemotherapy for recurrent diffuse large B cell lymphoma like ICE protocol.
after another course of chemotherapy, you might benefit from consolidative radiation to the spleen since this seems to be the place where the lymphoma is hiding out
it could be sort of a sanctuary site in the spleen where the chemo isn't getting into.
it is not typically known to be a sanctuary site
but radiation can be used there to kill lymphoma. you haven't had that treatment yet.
let me know if you have questions.