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My wife is going through IVF embryo transfer hopefully on…

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Hello. My wife is...

Hello. My wife is going through IVF embryo transfer hopefully on Friday. She had her period on 11/27. The MD then had her start Lupron 10mg Daily, estradiol 4mg Daily, enoxaparin 40mg daily, and aspirin 81mg and prednisone 25mg Daily.. After starting the regimen, 7 days into the regimen, she started bleeding like a regular period. We contacted the MD , who tripled the dose of Estradiol to 12mg Daily . My wife took it for 3 days and we are now out of Estradiol. Her bleeding stopped the following day after starting the 12mg.We have tried reaching the MD to no avail. My wife has a pack of Microgestin 1/20, which is she used to use. Is it ok for her to take the Microgestin to substitute the Estradiol while we reach the MD?

Doctor's Assistant: Have you been keeping a personal medical record?

Just the IVF specialist.

Submitted: 2 months ago.Category: OB GYN
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Answered in 3 minutes by:
12/10/2017
OB GYN Doctor: Dr. J, Board Certified OB/GYN replied 2 months ago
Dr. J
Dr. J, Board Certified OB/GYN
Category: OB GYN
Satisfied Customers: 405
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Hi there. Board-certified obgyn here. Preparing a response and will be with you shortly.

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OB GYN Doctor: Dr. J, Board Certified OB/GYN replied 2 months ago

The estradiol is just one hormone - estradiol. Microgestin has estradiol, and a second hormone which is called progesterone. I would not use the microgestin to replace the estradiol, because you'd be adding a separate hormone on which could potentially affect the hormonal milieu your doctor is trying to create before the embryo transfer.

I would also add that this is a totally appropriate scenario to call your doctor. They should have an answering service, or a nursing call line where you can reach someone who can help you or call out more estradiol for you. Is there any way you can keep trying?

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Customer reply replied 2 months ago
That has been my concern. The Microgestin has norethinodrone. Which is why I paused. The MD is out of Barbados and we have not been able to reach her. I will keep trying. I guess they told us to take the Estradiol to grow the lining of the Uterus. Would norethinodrone help with this or negatively affect it?
OB GYN Doctor: Dr. J, Board Certified OB/GYN replied 2 months ago

Norethindrone (a type of progesterone) usually thins the lining. That being said, I do not have infertility subspecialty training as I'm assuming your infertility doc does, so I'm not sure what the usual protocol is for such scenarios.

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