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Has she had nerve conduction tests (NCV/EMG)? This test will tell you if there is nerve damage and at what level. They should do both her legs and her arms to look for evidence of a peripheral neuropathy.
Try to get the results of the nerve test. If normal, see a vascular surgeon first as she might have venous insufficiency which can cause these types of problems even withouit blockages in the arteries or veins. If a vascular surgeon says it is not vascular, consult with a cardiologist to make sure it is not from heart failure. At the end of her work up, if no answer is found, a neurologist can do a nerve biopsy to make sure she does not have a small fiber neuropathy.
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