Neurology

Ask a neurologist. Get answers to your neurology questions.

Ask a Doctor,
Get an Answer ASAP!

My wife's creatin level (cpk) test was 278 (range24-170)-she…

Customer Question
my wife's creatin level (cpk)...
my wife's creatin level (cpk) test was 278 (range24-170)-she has been unable to walk and getting worse these past 2 years-she takes crestor and celebrex-she has frequency of urination-swelling of her ankle and legs-she takes lasix and vesicare.she has a physical trainer twice weekly trying to build up her leg muscles. i have taken her to many clinics and rehabs over the past 5 years (5 yrs ago a metal ladder hit her on her head).every doctor and pt has no answer why she cannot walk. do you have any ideas?
Submitted: 8 years ago.Category: Neurology
Show More
Show Less
Ask Your Own Neurology Question
Answered in 12 minutes by:
6/29/2010
Neurologist: Dr. Sophie :: Neurology, Neurologist (MD) replied 8 years ago
Dr. Sophie :: Neurology
Dr. Sophie :: Neurology, Neurologist (MD)
Category: Neurology
Satisfied Customers: 2,951
Experience: Neurology, Clinical Neurophysiology :: U of California
Verified
Hello,

How long has she been on Crestor?

Are her legs tight or stiff in addition to being weak?

Does she have any numbness or pain?

What was her neurological exam like -- do you know?

What test has she had so far? (MRIs, EMG, what blood tests??)
Ask Your Own Neurology Question
Customer reply replied 8 years ago

1. on crestor for 2 years-stopped crestor yesterday-found out can effect creatin level

2.yes, legs and knees very tight and stiff,but not weak-her trainer said they are strong

3 no numbness

4 had nerve conduction test -results-negative-sciatic problems which we knew

5 tests run-mri's,x-ray on knees,following blood tests: b12&folate,giladin ig/a/eia,tsh,t4 direct s,creatin kinase,magnesium serum,triiodthyronine,antipancreatic islet,ife pe,basic metabolic panel,ana c reflex,rheumatoid arthritic factor,uric acid,sed rate westergren,aldolase, & c-reactive protein. anti gad & anti amphiphysin lab did not know how to do those last tests. all results normal except creatin kinase at 280

Neurologist: Dr. Sophie :: Neurology, Neurologist (MD) replied 8 years ago


Hello again,

It sounds like she had a lot of studies. Anti-GAD and anti-amphiphysin antibodies are usually send-out studies to larger labs like Athena Diagnostic and local labs are typically unable to process these requests. I would consider resending them.

Statin drugs have been long known to cause myopathy is susceptible patients and result in elevated CK. Your wife's CK elevation is mild and it is not what is causing her symptoms.

If she already had a thoracic and lumbar spine MRI and her EMG was OK, it suggests that the problem may be in the central nervous system -- the spinal cord. Having said that, EMG may miss abnormalities if the muscle areas sampled happen to be normal or borderline normal. Her current neurologist should consider spinal tap and muscle biopsy (after she has been off Crestor for a few months) to exclude inflammatory process in the CSF and metabolic disorder of the muscle. Infectious causes such as HTLV-1 myelopathy (screening blood test), hereditary form of spastic paraparesis and primary lateral sclerosis should also be considered.

Hope this helps. Please let me know if you have another question.

Ask Your Own Neurology Question
Neurologist: Dr. Sophie :: Neurology, Neurologist (MD) replied 8 years ago
I noticed you read my answer a while ago and did not post any further questions.

You also did not accept my answer.

If you have further questions, please ask. If not, I would appreciate if you clicked Accept.

Thank you.
Ask Your Own Neurology Question
Was this answer helpful?

How JustAnswer works

step-image
Describe your issueThe assistant will guide you
step-image
Chat 1:1 with a neurologistLicensed Experts are available 24/7
step-image
100% satisfaction guaranteeGet all the answers you need
Ask Dr. Sophie :: Neurology Your Own Question
Dr. Sophie :: Neurology
Dr. Sophie :: Neurology
Dr. Sophie :: Neurology, Neurologist (MD)
Category: Neurology
Satisfied Customers: 2,951
2,951 Satisfied Customers
Experience: Neurology, Clinical Neurophysiology :: U of California

Dr. Sophie :: Neurology is online now

A new question is answered every 9 seconds

How JustAnswer works:

  • Ask an ExpertExperts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional AnswerVia email, text message, or notification as you wait on our site. Ask follow up questions if you need to.
  • 100% Satisfaction GuaranteeRate the answer you receive.

JustAnswer in the News:

Ask-a-doc Web sites: If you've got a quick question, you can try to get an answer from sites that say they have various specialists on hand to give quick answers... Justanswer.com.
JustAnswer.com...has seen a spike since October in legal questions from readers about layoffs, unemployment and severance.
Web sites like justanswer.com/legal
...leave nothing to chance.
Traffic on JustAnswer rose 14 percent...and had nearly 400,000 page views in 30 days...inquiries related to stress, high blood pressure, drinking and heart pain jumped 33 percent.
Tory Johnson, GMA Workplace Contributor, discusses work-from-home jobs, such as JustAnswer in which verified Experts answer people’s questions.
I will tell you that...the things you have to go through to be an Expert are quite rigorous.

What Customers are Saying:

I feel so much better today, and upon further investigation believe that there is a chance that the responses I got saved me from a serious, even life threatening situation. I am very grateful to the experts who answered me.

Susan O.USA

Wonderful service, prompt, efficient, and accurate. Couldn't have asked for more. I cannot thank you enough for your help.

Mary C.Freshfield, Liverpool, UK

This expert is wonderful. They truly know what they are talking about, and they actually care about you. They really helped put my nerves at ease. Thank you so much!!!!

AlexLos Angeles, CA

Thank you for all your help. It is nice to know that this service is here for people like myself, who need answers fast and are not sure who to consult.

GPHesperia, CA

I couldn't be more satisfied! This is the site I will always come to when I need a second opinion.

JustinKernersville, NC

Just let me say that this encounter has been entirely professional and most helpful. I liked that I could ask additional questions and get answered in a very short turn around.

EstherWoodstock, NY

Thank you so much for taking your time and knowledge to support my concerns. Not only did you answer my questions, you even took it a step further with replying with more pertinent information I needed to know.

RobinElkton, Maryland

< Previous | Next >

Meet the Experts:

Dr. Mark

Dr. Mark

Neurologist (MD)

2,191 satisfied customers

Neurosurgeon - Brain, spine, and peripheral nerve surgery

Jack Scariano Jr

Jack Scariano Jr

Neurologist (MD)

1,056 satisfied customers

Board Certified Neurology 1982 30 years experince. Also expert in Pain Medicine

Dr. Bob

Dr. Bob

Neurologist (MD)

3,773 satisfied customers

Neurology & Int Medicine (US Trained): 20 yrs experience

healthydoc

healthydoc

Board Certified Physician

1,851 satisfied customers

Board Certified U.S. Neurologist

Dr. F

Dr. F

Board Certified MD

266 satisfied customers

Neurosurgeon with more than 20 years experience in practice and teaching.

Phytube.com

Phytube.com

Neurologist (MD)

86 satisfied customers

Pediatric Neurology and Developmental Medicine with Special Research In Pain Medicine/Medications

Stroke Doc

Stroke Doc

Board Certified Physician

51 satisfied customers

I am board-certified in Neurology and the subspecialty Vascular Neurology.

< Previous | Next >

Related Neurology Questions
My daughter is 49 she was diagnosed with Neurofibromatosis
My daughter is 49 she was diagnosed with Neurofibromatosis @46.She had surgery on her spine at the time but the surgeon Dr Elad Levy could not remove any of the tumors. He said they had been there a l… read more
Dr. Mark
Dr. Mark
Neurologist (MD)
Doctoral Degree
2,191 satisfied customers
My wife had a stroke on October 23rd, we are from Canada,
My wife had a stroke on October 23rd, we are from Canada, but we have a house in Utah. My wife is taking rehab at the intermountain hospital in St Georgr Utah. The p, t is a graduate from neuro Ifrah … read more
Dr. Arun Phophalia
Dr. Arun Phophalia
Consultant Surgeon and Sports Medicine
Post-Doctoral Degree
34,353 satisfied customers
My mother was hospitalized Anne Arundel Medical Center on
My mother was hospitalized Anne Arundel Medical Center on July 13 weakness in her left arm and leg.The hospital did MRI and found there was a bleed on the right front lobe. They never called it a hemm… read more
Dr. Thomas, MD
Dr. Thomas, MD
2,227 satisfied customers
My wife fell on July first and broke bone in her foot. The
My wife fell on July first and broke bone in her foot. The doctor told her when he applied the air cast to keep weight off it for a week ( which is today). she has scheduled meeting with the doctor on… read more
Dr.Amita
Dr.Amita
Doctoral Degree
1,587 satisfied customers
My wife had a fall a month ago and fracture her left pubic
My wife had a fall a month ago and fracture her left pubic ramus. It has been healing very nice but ever since the fall she is having pain on her left leg either above the knee or under. The pain kind… read more
neuromd2012
neuromd2012
Neurologist/Staff Clinician
Doctoral Degree
2,815 satisfied customers
My Mother is almost 101 years old. She fell prior to
My Mother is almost 101 years old. She fell prior to Christmas and injured her left side in general and particularly her left ankle. She was able to walk and move her ankle in circular motions. Didn't… read more
Dr. D. Love
Dr. D. Love
Doctoral Degree
10,423 satisfied customers
My grandma got stroke two months ago. Before that she had
My grandma got stroke two months ago. Before that she had atrial fibrillation over 5 decades. The doctor told me it is the AF that caused the disorder. Three quarters of her right brain is influenced … read more
neuromd2012
neuromd2012
Neurologist/Staff Clinician
Doctoral Degree
2,815 satisfied customers
My mother had a stroke she is 83 yrs old. It left her rt.
My mother had a stroke she is 83 yrs old. It left her rt. side unable to use and her speech very limited. her rt. arm is very painful to do anything at all with it. We can't even use it to help move h… read more
Dr. Bob
Dr. Bob
Neurologist (MD)
Doctoral Degree
3,773 satisfied customers
My wife (70) had an event (aphasia (both), visual, and
My wife (70) had an event (aphasia (both), visual, and confusion) in May. At the ER the CT was neg and they gave her tPA. Consequently she had a huge subarachnoid hemorrhage and was trf to the higher … read more
neuromd2012
neuromd2012
Neurologist/Staff Clinician
Doctoral Degree
2,815 satisfied customers
My 84 year old mother is recovering from GBS, she's in a
Hello...my 84 year old mother is recovering from GBS, she's in a nursing home. It started with the stomach flu and her Dr. said she had Diverticulosis. She suddenly couldn't stand and had severe pain … read more
Dr. Thomas, MD
Dr. Thomas, MD
2,227 satisfied customers
My mom was just diaginosed with a sacrum fracture. She is 79
My mom was just diaginosed with a sacrum fracture. She is 79 years old and in extreme pain which goes down into her ankle. She can't get in to see the spine doc till next week. What can I do to help h… read more
neuromd2012
neuromd2012
Neurologist/Staff Clinician
Doctoral Degree
2,815 satisfied customers
My wife during the past few weeks has complained of pain in
My wife during the past few weeks has complained of pain in her one leg. She has varicose veins in both legs and the discoloration is quite pronounced - purple, bruise-like. Yesterday while swimming i… read more
Dr. Mark
Dr. Mark
Neurologist (MD)
Doctoral Degree
2,191 satisfied customers
Had 3 stents put in 2005 and was on 40 mg of simostation rom
Had 3 stents put in 2005 and was on 40 mg of simostation rom 05 till 08. Developed severe muscle pain in 08. Learned of Rhabdomyolisis and possible death and quit statins. Had 6ix back surgeries, fusi… read more
Pauline
Pauline
Doctor
Bachelor Degree
776 satisfied customers
My mother just had back surgery - partial laminectomy to
My mother just had back surgery - partial laminectomy to deal with spinal stenosis and arthritis. L3/L4 & l4/l5 - very successful. However, since the surgery she has an issue with her right leg. It is… read more
Dr. Bob
Dr. Bob
Neurologist (MD)
Doctoral Degree
3,773 satisfied customers
My partner has just had surgery on her back she had a
my partner has just had surgery on her back she had a ruptured disk on the left side then the right side failed and then she had surgery on the right side since the second surgery she has had really s… read more
Dr. Mark
Dr. Mark
Neurologist (MD)
Doctoral Degree
2,191 satisfied customers
My wife age 85 suffers from non-diabetic lsrpn. She was
My wife age 85 suffers from non-diabetic lsrpn. She was perfectly healthy Jan 2010. colonoscopy in Feb./ back pain in March/Shingles in April(she had the shot previously). nerve block in April./ three… read more
RH
RH
Doctor of Medicine
1,944 satisfied customers
My mom, age, had a major stroke last Nov. With intense rehab
My mom, age 69, had a major stroke last Nov. With intense rehab she regained her speech and use of her left leg (with a quad cane). Her left arm/hand began to be able to squeeze slightly. After stayin… read more
HouseDoc
HouseDoc
Attending Neurologist
Doctoral Degree
1,313 satisfied customers
My monther had brain stroke 3 years ago, but fully recovered
My monther had brain stroke 3 years ago, but fully recovered (except her right side was weak, but she could move her hand 80% and she could walk - use her leg 20%). She had been complaining knee pain … read more
RH
RH
Doctor of Medicine
1,944 satisfied customers
Disclaimer: Information in questions, answers, and other posts on this site ("Posts") comes from individual users, not JustAnswer; JustAnswer is not responsible for Posts. Posts are for general information, are not intended to substitute for informed professional advice (medical, legal, veterinary, financial, etc.), or to establish a professional-client relationship. The site and services are provided "as is" with no warranty or representations by JustAnswer regarding the qualifications of Experts. To see what credentials have been verified by a third-party service, please click on the "Verified" symbol in some Experts' profiles. JustAnswer is not intended or designed for EMERGENCY questions which should be directed immediately by telephone or in-person to qualified professionals.

Disclaimer: Information in questions, answers, and other posts on this site ("Posts") comes from individual users, not JustAnswer; JustAnswer is not responsible for Posts. Posts are for general information, are not intended to substitute for informed professional advice (medical, legal, veterinary, financial, etc.), or to establish a professional-client relationship. The site and services are provided "as is" with no warranty or representations by JustAnswer regarding the qualifications of Experts. To see what credentials have been verified by a third-party service, please click on the "Verified" symbol in some Experts' profiles. JustAnswer is not intended or designed for EMERGENCY questions which should be directed immediately by telephone or in-person to qualified professionals.

Show MoreShow Less

Ask Your Question

x