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Hello and thank you for requesting me. I am so sorry that you are suffering from this level of depression, I can understand why you would want it to be resolved more quickly. The Cymbalta, Effexor XR, and the Fetzima are all SNRI antidepressants, so at least you are in the same class of antidepressants. Effexor XR has a better track record for treating depressive disorders
compared to Fetzima, but this is also due to the fact that Fetzima is relatively new and has only come on the market in 2013-2014, so there is still a lack of peer reviewed research on Fetzima compared to Effexor. If you want my opinion, I think it would be better to continue with your transition to the Effexor as there is more factual evidence to support its use and effectiveness when treating a depressive disorder compared to the Fetzima.
If the Effexor does not work than you can try the Fetzima if you like. Or alternatively there is a mood stabilizer called Lamictal that is used primarily to treat Bipolar
Depression or resistant cases of Depression and that can be a good alternative for you. In addition, switching from Abilify to Latuda can also prove more effective as Latuda has a greater effectiveness rate in treating depressive symptoms. I am only mentioned these other alternatives as future options "just in case."
I hope this answers your question and gives you some guidance on this issue. I truly wish you all the best with your treatment and I hope that the Effexor helps to lessen your depressive symptoms.
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