Hi! I'll be glad to be of help with this issue.
I can imagine how frustrating this situation must be for you. You were taking Cymbalta for only 3 months and now after 3 days of tapering and 4 days of being off completely, you are still feeling the sexual side effects. And Cymbalta has a relatively short half life of about half a day. The half life means that after about 12 hours, the dosage you took is half flushed out of your system. Then another 12 hours, half of that half is gone, etc. So by now, there are only traces of the drug in your system. So you would think any side effect would be over by now.
And this is actually the key to my answer to you that you need to consider and think about. Medications don't work in a strictly mechanical way. It's very frustrating, I know. But our bodies, even after 3 months, get adjusted to a certain chemical response system and once our bodies are adjusted, it can take a while to override that response with a new response. Many people have felt side effects for 6 weeks after the tapering down is completed. But you know, we are each so different and our brains are such complex systems that it is so hard to know if that is how long it will take for you or not.
Wellbutrin is an antidepressant that has been prescribed for a number of years to address this specific issue you're having. Research, while not conclusive, has found that Wellbutrin together with SSRIs and SNRIs (Cymbalta is an SNRI) can counteract the sexual side effects of the SNRI. And that this counter-effect for sexual side effects is also present when Wellbutrin replaces the SNRI.
While, as I said, the research is not large scale trials, doctors have been prescribing Wellbutrin for this purpose and the anecdotal evidence has been positive. So I am relating this to you in case you wish to bring it up with your doctor as a possibility to help in counteracting the sexual side effects. You and your doctor might consider putting you on Wellbutrin for a limited time to see if it will help.
Okay, I wish you the very best!
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