How JustAnswer Works:
  • Ask an Expert
    Experts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional Answer
    Via email, text message, or notification as you wait on our site. Ask follow up questions if you need to.
  • 100% Satisfaction Guarantee
    Rate the answer you receive.
Ask Dr. Kaushik Your Own Question
Dr. Kaushik
Dr. Kaushik, Psychiatrist
Category: Mental Health
Satisfied Customers: 4672
Experience:  MD Psychiatry
Type Your Mental Health Question Here...
Dr. Kaushik is online now
A new question is answered every 9 seconds

At present I am taking Wellbutrin SR 150 mg twice a day, and

This answer was rated:

At present I am taking Wellbutrin SR 150 mg twice a day, and 20 mg of Prozac in the morning only. I have been on both for the last several years, and increased the Prozac from 10-20 about a year ago. I think I need something different. I don't feel much of anything. I procrastinate terribly, have trouble doing or getting things done. No motivation or drive. I sleep a lot more or want to sleep more. I just feel flat. What might be a better anti-depressant to take? I am a 56 year old male and have been on the antidepressants for the last 11 years. As I get older, I think it gets worse. Any suggestions?

Greetings !

Welcome to the site.

I am Dr. Kaushik and i believe i can help you with your problem.

Well it seems like after long term use of these two drugs your body system has developed what is called as Increased Tolerance / Resistance which has made them ineffective .

So in this situation there are usually two strategic options that can be done --

1) To optimize the doses of both the anti depressants like raising the wellbutrin sr to 300 mg / day and prozac to 40 -60 mg / day , this is done in order to extract maximum output from the drugs while which are raised to the maximum recommended doses.

2) To replace one or both the drugs by other potential anti depressants. Here what you can do is that you raise the wellbutrin sr to 300 mg/ day while replace Prozac by another effective anti depressant like remeron ( mirtazapine) at dose of 15-45 mg / day or Cymbalta ( duloxetine) at dose of 40-60 mg / day.

So kindly discuss this with your treating doctor and choose any one of them to get your symptoms under control and get back to the previous symptom free state.

I hope this helps.

Wish you all the best.

Please kindly leave a Positive rating if you are satisfied with the answer.

If there is any further assistance needed please feel free to ask using the reply button.


Dr. Kaushik and other Mental Health Specialists are ready to help you
Customer: replied 4 years ago.
Sorry, I just can't afford a bonus. And thank you so much.

No problem.

You take care.

Wish you all the best.