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Ask Dr. Ed Wilfong Your Own Question
Dr. Ed Wilfong
Dr. Ed Wilfong, Psychologist
Category: Mental Health
Satisfied Customers: 1528
Experience:  Twenty-five years treating all ages; Specialities: psychopharmacology & diagnosis, MMPI-2, testing.
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Just a quick question about dosulepin; I've been taking it

Resolved Question:

Just a quick question about dosulepin; I've been taking it at 150mg at night for about 20 years to treat ongoing depressive episodes. I've heard that it be damaging to the heart at higher dosage - is this classified as a higher dose? I'd really like to come off it and fly 'solo' as it were but it wasn't good last time- i had a really unpleasant bout. My GP says it obviously 'doesn't suit you to come off it' and just recommended that I go back to 150mg. I've tried several ssri's as alternatives, but the side effects from these are difficult to cope with, and lead a reasonable life. Any thoughts on where to go from here would be gratefully received.
Submitted: 6 years ago.
Category: Mental Health
Expert:  Dr. Ed Wilfong replied 6 years ago.
Dr. Ed Wilfong :

150mg is normal dose. 300 is high. It is a tricyclic. Most patients who used to use are on SSRI's now, but your dose is OK


So what would your advice be to enable me to come off them?

Dr. Ed Wilfong :

Steve- dose is fine. Just a drug that is not used in US. IF you want to try SSRI, talk to doctor about transition. I just saw you had poor reaction to SSRI's - sorry I missed that initially. I don't see any harm on staying on the current medication. It is mostly and individual tolerence to certain class of medication, and if tricyclic is better for you, I would stick with it. In my experience, alarming stories on internet are much more frequent than in actual practice. Given that you are at lowest recommended dose, not a high dose, I would not worry about getting off of it or changing medications.


Thanks for your reassurance, much appreciated!


Thanks for your reassurance,

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