My question involves sleep, PTSD, and medications.
I am recovering from long-term PTSD, and have long had sleep-maintenance insomnia
(wake up at 3:00 am - 5:00 am, and have trouble falling back asleep). Many studies link sleep disturbances and PTSD.
Robert Stickgold, [EMDR: A Putative Neurobiological Mechanism of Action, Journal Of Clinical Psychology, Vol. 58(1), 61–75 (2002)] makes a strong case that REM sleep is necessary to recover from PTSD. At my last polysomnograph in 2007, my total REM sleep was one-third of normal duration.
I take a lot of medications, and wonder how my cocktail might be adjusted to improve both my sleep and my PTSD recovery.
QAM I take:
Prozac, 40mg, which I probably don't need any more
Exforge (amlodipine and valsartran) for BP
QHS I take:
nadolol 80mg, for migraine prophylaxis
Depakote ER 1500mg, for sleep-maintenance insomnia
clonidine 0.3mg, reasons lost in history
clonazepam 1.5mg, reasons lost in history
PART A: might you change anything above to enhance my sleep and recovery from PTSD? (and why?)
PART B: I read in detail that prazosin is often effective for sleep and other symptoms of PTSD. What might you think of replacing one or more of the above with prazosin? (and why?)