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Dr. Vikas
Dr. Vikas, Psychiatrist
Category: Mental Health
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Experience:  MBBS ; M.D Psychiatry, MS. Health Informatics
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How do "brain shivers" (withdrawal symptom associated with

Resolved Question:

How long do "brain shivers" (withdrawal symptom associated with Effexor)last?
Submitted: 7 years ago.
Category: Mental Health
Expert:  Dr. Vikas replied 7 years ago.

Hello brooklyn,

This drug should always be tapered down to avoid withdrawal effects such as nausea, dizziness, stomach cramps, sweating, tingling sensations etc. There is no strict time duration for how long these withdrawal symptoms can last.

As this drug has half life of 7 -13 hours in body and any drug is flushed out from the body approx five times its half life, it may take 3 to 4 days to be removed from the body and these withdrawal effects if minor could last from 1 to 2 weeks.

But if the side effects are moderate or severe, in my view he should consult his treating doctor once again. Usual strategy is to restart the Effexor once again and than to taper it down slowly to avoid withdrawal if he don't want to continue this medicine anymore.
Many patients are able to tolerate 50% dose reduction for 3 days, then another 50% dose reduction for 3 days followed by discontinuation.

If you have any related query, please feel free to ask.

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