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Dr. Vikas
Dr. Vikas, Psychiatrist
Category: Mental Health
Satisfied Customers: 2253
Experience:  MBBS ; M.D Psychiatry, MS. Health Informatics
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Can naltrexone be taken with lexapro? would that be safe

Resolved Question:

can naltrexone be taken with lexapro? would that be safe
Submitted: 8 years ago.
Category: Mental Health
Expert:  Dr. Vikas replied 8 years ago.
Hello Mam,

There are some studies (Preclinical research and small human pilot studies) which suggest that greater suppression of drinking results with concurrent treatment with naltrexone and a serotonin reuptake inhibitor (Lexapro (escitalopram) is a SSRI).

I am giving you the link below of few of these studies.

open randomized study of the treatment of escitalopram alone and combined with γ-hydroxybutyric acid and naltrexone in alcoholic patients

(In this study, Lexapro was used with Naltrexone)

Naltrexone Is Associated With Reduced Drinking by Alcohol Dependent Patients Receiving Antidepressants

(Please consult your treating doctor before taking any such combination)

I hope it helps.

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