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I've been taking 60mg cymbalta at night for about 3 years…

Customer Question
I've been taking 60mg...

I've been taking 60mg cymbalta at night for about 3 years now. I also take 70mg of vyvanse every morning. The vyvanse I've been on for about 6 months now. It always makes me really tired and sleepy mid morning. Would it help if I took my cymbalta in the morning too - or would this just make me more sleepy? Also is it safe to take the two at the same time?

Doctor's Assistant: How is your mood? Are you experiencing regular sleep disturbances (e.g. trouble falling asleep, waking up early)?

Yes I have trouble falling asleep and then once I'm asleep I have a very hard time waking up.

Doctor's Assistant: Anything else in your medical history you think the Psychologist should know?

Not really - just tired a lot. No energy. But I've had bloodwork done and everything is good according to the doc.

Doctor's Assistant: In general, how has your health been lately?

Very good

Submitted: 11 months ago.Category: Medical
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Customer reply replied 11 months ago
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Answered in 36 minutes by:
9/21/2017
Doctor: Dr. Muneeb Ali, Doctor replied 11 months ago
Dr. Muneeb Ali
Category: Medical
Satisfied Customers: 10,282
Experience: MBBS, MD, MCCM. Currently working in Critical Care Medicine with 10 year experience in Medicine
Verified

Hi,

Welcome to JA and thanks for this question. Im sorry to hear about your symptoms. Actually using cymbalta with vyvnase is not recommended. Duloxetine (cymbalta) may increase the effects of lisdexamfetamine (vyvnase), and side effects such as jitteriness, nervousness, anxiety, restlessness, and racing thoughts have been reported. Combining these medications can also increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea.

So basically these two should not be used together, so using cymbalta in the morning with vyvnase is not recommended.

Do you have any more questions?

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