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Hello, this is Dr. David. I am reviewing your question now and will be with you momentarily.
you gave me the study where you had that data for discordance for lobular cancers when they metastasize.
we looked at a study which quoted those numbers.
I tried to find the study you posted in your questions to me.
you have way too many questions
I couldn't find the question.
you are so worried about PR changing before.
you had a period where you found a study showing that PR changing from chemo was a bad thing
and that PR negative means your cancer was going to come back and be more aggressive.
you read all of these studies.
I have told you my experience with lobular carcinoma patients and their mets already
I saw six patients, all had kept their ER and PR status.
I have told you already, it is not common for PR to turn negative at first metastasis.
you don't need to worry about mets.
you need to calm down your worries.
you don't have to worry about mets.
you don't have mets now
so there is nothing to biopsy to know if your PR is negative