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Stage 5 renal disease refers to the severity of the disease, as determined by the GFR. The GFR is a measure of the amount of blood filtered by the kidney. A normal GFR is 90 or above. A mild decrease in GFR is 60-90, and it is not considered to be chronic renal disease until the GFR is less than 60. Stage 5 renal disease is when the GFR is less than 15.
There is not a single reason for stage 5 renal disease, and the underlying cause will determine what, if any treatment may exist. For most causes of stage 5 renal disease, there is no cure, but there may be some interventions that can be done to limit progression of the disease. Diabetic kidney disease is one of the more common causes of stage 5 renal disease, and while there is no cure, appropriate treatment of the diabetes and ACE inhibitors or ARBs may help to limit progression of the disease process.
From the standpoint of kidney disease, a person with stage 5 disease can be considered for a transplant, but whether he would be eligible for a transplant would depend also upon an assessment of his other medical problems. Specifically, his cardiovascular disease may be an issue, but his Kidney doctor could discuss his case with his other doctors to assess whether he is a candidate.
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