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Family Physician
Family Physician, Doctor
Category: Medical
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Experience:  Emergency Medicine and Family Practice for over 26 years
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Dr., This article says that breast cancer stem cells in ER+

Customer Question

Dr. David,This article says that breast cancer stem cells in ER+ breast cancer are ER+. Do you think that means they have estrogen receptors? Do you think that means AI's work on them? Can I trust this articlez/
Submitted: 1 year ago.
Category: Medical
Expert:  Dr. David replied 1 year ago.

This is Dr. David

yes, your AI and zometa will work on these stem cells.

I don't know what article are you are talking about.

Customer: replied 1 year ago.
http://www.ncbi.nlm.nih.gov/pubmed/21459518this is the article: http://www.ncbi.nlm.nih.gov/pubmed/21459518I had thought that stem cells were all ER-, so AI's wouldn't work on them--but you seem to know that they can be ER positive and have AI's work?
Customer: replied 1 year ago.
do stem cells have estrogen receptors in ER+ cancers????
Expert:  Dr. David replied 1 year ago.

http://www.medical-hypotheses.com/article/S0306-9877(11)00130-7/pdf

I can't get the full article.

"Therefore, we hypothesize that the ER expression of BrCSCs depends on the original breast cancers."

it is a hypothesis.

we can't see stem cells.

it is a theoretical cell.

Customer: replied 1 year ago.
We concluded that the ER expression of BrCSCs in ER+ breast cancers is positive, while it is negative in ER− breast cancers. It also says the above.You think AI's work on stem cells?
Expert:  Dr. David replied 1 year ago.

you need to read the whole article

there is no conclusion which can be made

this is an article written by Chinese people

their English isn't the best.

Expert:  Dr. David replied 1 year ago.

stem cells is a theoretical cell which explains why 1.5% of patients per year have recurrence of their breast cancer after 5 years

so in these patients, the AI therapy didn't work.

Customer: replied 1 year ago.
you said above that AI's work on stem cells--please explain
Expert:  Dr. David replied 1 year ago.

stem cells is a theoretical cell which explains why 1.5% of patients per year have recurrence of their breast cancer after 5 years

we don't know what type of stem cell people can have

there are no scans which can see stem cells.

Customer: replied 1 year ago.
I can't pay for this. You changed your story. You started with AI's will work on these stem cells. And now you've changed it. I am sorry.