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This is Dr. Diego, experienced on Internal medicine, Pulmonary and Critical Care.
I understand your concerns. Do you have any other medical conditions? Do you take any other medications? Why do do take Penicillin VK?
Anxiety is a very rare side effect for penicillin VK. The best approach for now is to stop the penicillin VK. I don't see other medications or medical conditions that you have that could cause anxiety. Benadryl sometimes can cause anxiety too. For now stop benadryl and penicillin. Your symptoms should improve in the next 1-2 days. If your symptoms persist go to your PCP. Let me know if you have any other questions. Please rate my answer.