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Dr., I don't think I should look at that article. It may
Dr. David,I don't think I should look at that article. It may upset me. BUT, are you SURE it said that the entire LOBULAR cell cycle just takes 1-2 days? How did it say that? Can you give me the sente… read more
Dr. David
Dr. David
Board Certified Physician
Post-Doctoral Degree
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Dr., I know lobular cancer tends to be very ER+. But I also
Dr. David,I know lobular cancer tends to be very ER+. But I also know that breast cancer in general has less PR positivity. Do you think a bunch of lobular cancers are ER+ and PR-?… read more
Dr. David
Dr. David
Board Certified Physician
Post-Doctoral Degree
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Dr. Love, Here's another idea. Do you think this would help?
Dr. Love,Here's another idea. Do you think this would help? Can you find 5 and 10 year survival stats for lobular and ductal? If lobular is a lot worse it means the CTC's are wrecking everything.… read more
Dr. D. Love
Dr. D. Love
Doctor
Doctoral Degree
22,434 satisfied customers
Dr. Love, I'm so scared. I knew in my heart that this was
Dr. Love,I'm so scared. I knew in my heart that this was probably true. But now I've found all of these articles about breast cancer tumor dormancy.Here is one: http://www.ncbi.nlm.nih.gov/pmc/article… read more
Dr. D. Love
Dr. D. Love
Doctor
Doctoral Degree
22,434 satisfied customers
Dr., I am just remembering that my pathology report for my
Dr. David, I am just remembering that my pathology report for my ITC's said "some clumps". Is that bad? Does it mean they were dividing?… read more
Dr. David
Dr. David
Board Certified Physician
Post-Doctoral Degree
63,429 satisfied customers
Dr. Love, This is another scary article that shows that the
Dr. Love, http://www.biomedcentral.com/content/pdf/1471-2407-12-190.pdf This is another scary article that shows that the positive cells change to negative itc's (see chart). I am so disappointed and … read more
Dr. D. Love
Dr. D. Love
Doctor
Doctoral Degree
22,434 satisfied customers
Dr., Here is a different study that says the same thing.
Dr. David, Here is a different study that says the same thing. There is a table that shows most of the DTC's being negative. Do you think this is a good study? I am scared. Do you think that dtc's cha… read more
Dr. David
Dr. David
Board Certified Physician
Post-Doctoral Degree
63,429 satisfied customers
Dr. Love, This is a table from the article I sent you a few
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614509/table/T3/ Dr. Love, This is a table from the article I sent you a few days ago. I had always thought that with my strong estrogen positivity that al… read more
Dr. D. Love
Dr. D. Love
Doctor
Doctoral Degree
22,434 satisfied customers
Dr. Love, Here is an article that says that ITC's switch
Dr. Love, Here is an article that says that ITC's switch from being estrogen positive to being estrogen negative. It is very scary. Plus it says that 40% of ITC's switch to HER2+. Do you think this is… read more
Dr. D. Love
Dr. D. Love
Doctor
Doctoral Degree
22,434 satisfied customers
Dr., Tell me why that article I sent you last night isn't a
Dr. David, Tell me why that article I sent you last night isn't a bad thing. It has the positive estrogen receptors causing negative mets A LOT of the time. AND it says that in 40% of ITC's, the HER2 … read more
Dr. David
Dr. David
Board Certified Physician
Post-Doctoral Degree
63,429 satisfied customers
Dr., Thlis article is really scary. Would you trust it?
Dr. David, Thlis article is really scary. Would you trust it? http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614509/… read more
Dr. David
Dr. David
Board Certified Physician
Post-Doctoral Degree
63,429 satisfied customers
Dr., Can you find me a really reliable article that gives
Dr. David, Can you find me a really reliable article that gives the percentage of breast cancer patients that have itc's or dtc's in their bone marrow? I'm finding all different numbers. There is a 20… read more
Dr. David
Dr. David
Board Certified Physician
Post-Doctoral Degree
63,429 satisfied customers
Dr., I have been reading about how estrogen receptors mutate
Dr. David, I have been reading about how estrogen receptors mutate so that they don't need estrogen anymore. Then the AI's don't work. This would be particularly bad for me, because I have the ITC's. … read more
Dr. David
Dr. David
Board Certified Physician
Post-Doctoral Degree
63,429 satisfied customers
Dr., Can you remind me what percent of the time AI's work?
Dr. David, Can you remind me what percent of the time AI's work? It seems they should work all the time. Do you think when they don't work, it's because of ITC's?… read more
Dr. David
Dr. David
Board Certified Physician
Post-Doctoral Degree
63,429 satisfied customers
Dr., Tell me the reason, again, that a rogue itc (from
Dr. David, Tell me the reason, again, that a rogue itc (from BEFORE the aromatase inhibitors started) isn't going to give me mets?… read more
Dr. David
Dr. David
Board Certified Physician
Post-Doctoral Degree
63,429 satisfied customers
Dr., That thing I sent you last night said it was good to
Dr. David, That thing I sent you last night said it was good to have single cell itc's and bad to have clusters. I thought I only had single cells, because my second bone biopsy said "scattered" and "… read more
Dr. David
Dr. David
Board Certified Physician
Post-Doctoral Degree
63,429 satisfied customers
Dr. Love, Do you know anything about isolated tumor cells in
Dr. Love, Do you know anything about isolated tumor cells in the bone marrow in breast cancer patients? Apparently they are fairly common. They are not considered metastases. I have them, and they are… read more
Dr. D. Love
Dr. D. Love
Doctor
Doctoral Degree
22,434 satisfied customers
Dr., I know that ITC's often remain dormant. My ITC's tested
Dr. David, I know that ITC's often remain dormant. My ITC's tested ER positive. How likely is it for them to mutate and become negative?… read more
Dr. David
Dr. David
Board Certified Physician
Post-Doctoral Degree
63,429 satisfied customers
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