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Amitiza dose more than 48 mcg daily is considered too much.
Acute ingestion can cause headache, stomach pain, nausea, vomiting, diarrhea, palpitation, drop in blood pressure.
If you have these symptoms you should go to the ER for further evaluation.
The effect Amitiza usually passes within 24 hours given the short healf live ( less than 2 hours).
You should also discuss with your doctor.
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Yes you should.
You need to be checked out tonight.
You will need IV fluids also.