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This is usually a sign of peripheral neuropathy
There are many causes of peripheral neuropathy, the most common ones are vitamin B 12 deficiency, hypothyroidism
, diabetes mellitus and idiopathic (that is the cause can not be ascertained most of the times).
Once the cause of the neuropathy is established the treatment can be aimed at correcting the cause while providing symptomatic treatment for the aches and restlessness.
For example, if there is vitamin B 12 deficiency, the vitamin is replaced by oral or injectable supplements and a nerve membrane stabilizer like Gabapentin or Pregabalin is given to relieve the symptoms.
Another cause of wrist pain at night is carpal tunnel syndrome. This is when the median nerve is compressed in the wrist under the tendons and usually requires a surgical intervention
to relieve the symptoms and decompress the nerve.
I would suggest that you visit your PCP and have this evaluated, since this requires treatment as it is impairing your quality of life.
Hope this helps.
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