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Dr Basu
Dr Basu, Experienced Specialist
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Experience:  MD
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Dear Doctor, I've been taking 50mg of zoloft for 5 or 6

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Dear Doctor,
I've been taking 50mg of zoloft for 5 or 6 years. Recently had symptoms of extreme fatigue,nausea and weakness.Looked up the side effects of zoloft and realized they all related to me;dry mouth,body aches, headache,nausea and dizziness.At first my doctor thought it was hyponatremin but blood work did not indicate this. There was a slight elevation in the liver enzyme that he was not concerned with.
My problem and question now is although I've been off zoloft for 5 days I still feel awful,especially with the nausea, headache and fatigue and don't know what to do from here.The doctor said their was no need to taper.
Your opinion would be very appreciated.
Thank You,
The views expressed by me are for educational purposes only and do not establish a doctor patient relationship.
Hi there,
This is Dr. D.J., experienced Internal Medicine Specialist.
I am here to address your concerns and provide great service.
Zoloft is known to cause these gastrointestinal symptoms.
These symptoms can persist for 2-3 weeks even after discontinuing zoloft.
Since you were on zoloft such a long time, this is difficult during early days following discontinuing it.
But, you will definitely improve gradually over time.
Liver problem is another possibility although your enzymes are not that elevated.
Gallbladder disease also can cause elevated liver enzymes and these symptoms.
Pancreatitis is another possibility.
Thyroid gland disorder is also in the differential, especially hypothyroidism.
I will suggest an ultrasound of the abdomen to rule out gallbladder and pancreas problem.
Serum TSH level should be checked for thyroid problem.
Liver enzymes should be repeated if your symptoms do not show signs of improvement in next one week.
Best wishes
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