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Dr. Rick, MD
Dr. Rick, MD, Board Certified MD
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Experience:  20+ years as a doctor. Internal Medicine Internship in NYC
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My wife has an allergic reaction to epogene, but not to procrit.

Resolved Question:

My wife has an allergic reaction to epogene, but not to procrit. Has anyne else
reported this?
Submitted: 5 years ago.
Category: Medical
Expert:  Dr. Rick, MD replied 5 years ago.

RickMD :

I am online and happy to help you with your question today.

RickMD :

Yes, this has been reported. The two medicines,while similar, have different chemical structures. This difference can have very different effects on the immune system of some patients.

RickMD :

Procrit is made using recombinant DNA technology and is identical to human erythropoietin and, as as such is highly hypo-allergenic.

RickMD :

Here is a very good article that investigated just this issue:

RickMD :

Curr Med Res Opin. 2003;19(5):430-2. Epoetins: differences and their relevance to immunogenicity. Haselbeck A.

RickMD :

Does this make sense to you?

RickMD :

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Let me know if you have further questions.

RickMD :


I see that you are offline. I'll switch over to the Q&A system. This system works a lot like 'text messaging' but an email is sent to each of us anytime something is posted to this thread. We can continue to work on your question there..... :)

Expert:  Dr. Rick, MD replied 5 years ago.
I hope your wife continues to do well on the Procrit. Have a good day :-)
Customer: replied 5 years ago.

I need a copy of the Curr Med Res Opin. indicated in your reply.



Expert:  Dr. Rick, MD replied 5 years ago.
Ok. Let me see if I can get you at link to the article. BRB
Expert:  Dr. Rick, MD replied 5 years ago.
here is the link to the abstract of the article. I am unable to find a free source for the complete text but you may be able to contact one of the authors for a copy:

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