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DrRussMD, Board Certified Physician
Category: Medical
Satisfied Customers: 64647
Experience:  Internal Medicine--practice all of internal medicine, all ages, family, health, prevention, complementary medicine, etc.
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After a routine blood test my doctor called me back in for a

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After a routine blood test my doctor called me back in for a another round of blood test because of a elevated protein level, that test revealed the following,total serum protein 8.5, albumin 4.2, alpha 1 globulin 0.2, alpha-2 0.6, beta globuli 0.8, Gamm Globulin 2.6 high.
M-spike 2.0, globulin total 4.3, ag ratio 1.0.
After reading around on the internet I am very scared about the m-spike, I really feel okay, only a little fatigue, nothing to bad
I have a appointment next week with a hematoligist, I am so nervous I feel like I am creating symptoms in my head that I was not having a couple of days ago.
Submitted: 6 years ago.
Category: Medical
Expert:  DrRussMD replied 6 years ago.
can you type in reference ranges for accuracy
it looks like only the total protein and gamma globulin are high, which is non-specific at this point
Customer: replied 6 years ago.
on the ones that are flagged high
gamma globulin 2.6 ref range 0.5 - 1.6
total protein is 8.5 range shows 6.0 - 8.5
m-spike shows no reference, this is what is really scarring me.
Also my wbc seems to be low at 3.1 range shows 4.0 - 10.5
Expert:  DrRussMD replied 6 years ago.
The detection of the M spike is the concern, but not definitive, that is why there is no reference range on that
The totally protein is normal more or less.
The gamma globulin non-specific.

So, nothing definitive here.
Further testing to rule out multiple myeloma is what might calcium levels, renal function tests, urine to try to detect k and l light chains.

Your M spike however is less than three which implies a monoclonal gammopathy of unknown significance, so more than likely you do not have MM.j
If any question a bone marrow test, but doubt this will be necessary.

Even "smoldering" myeloma would generally have an M spike above three.
I am not saying don't follow with the heme doc, but you are probably OK
good luck

Customer: replied 6 years ago.
what about the white blood count of 3.1
Expert:  DrRussMD replied 6 years ago.
Not low enough to be specific.
I would have that repeated.
It can be lowered in MM, however, you have no findings to co-oberated this...such as elevated calcium which would be more definitive.
3.1 can be from recent viral infection, medications, etc.

Good luck again

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