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If the cause of the enlarged lymph nodes is related to bacterial induced infection and/or inflammation, then the sulfameth/trimethoprim
(Bactrim or Septra) would be effective against the sensitive bacteria. Considering that you have chronic lymphadenothy, it is also possible that there is another contributing underlying autoimmune
related chronic inflammation and/or infection. Tests such as ESR, C-reactive protein, ANCA panels and complete blood count with differentials will help exclude this possibility. It is likely that in addition to the Bactrim or Septra, that you would need other medications, including anti-viral
and/or antifungal medication if the biopsy of the enlarged lymph node reveal any other causative agent. In the meantime, I suggest that you continue the use of the medication (Bactrim or Septra) given by your doctor, and request for closer evaluation if the condition fails to reduce.
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