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Dr. D. Love
Dr. D. Love, Doctor
Category: Medical
Satisfied Customers: 18462
Experience:  Family Physician for 10 years; Hospital Medical Director for 10 years.
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What are the main differences between Coreg CR and Diovan when

This answer was rated:

What are the main differences between Coreg CR and Diovan when trying to lower blood pressure?

Which one has more side effects?

Why does Coreg CR cause weight gain?

Which one is "easier" on your liver?

Thank you for your question.


Coreg is in a class of medicines called β-blockers, which work by slowing the heart and lowering blood pressure. Diovan is in a class called angiotensin receptor blockers, which blocks a hormone that is involved in the regulation of blood pressure. Usually, both are well tolerated and have a low incidence of side effects, although the Diovan has a slightly lower side effect profile. β-blockers are recommended as first-line agents, because they also reduce the likelihood of cardiac events. Diarrhea and nausea are two of the more common side effects of Coreg. All β-blockers can cause fluid retention; indeed all blood pressure medicines that do not have a diuretic effect can cause fluid retention. Coreg, by slowing the heart, may limit a person's exercise capacity. Weight gain can be related to fluid retention or to decreased exercise. Angiotensin blockers have a mild diuretic effect, so tend to not cause fluid retention. Diovan is more likely to affect the liver, but that side effect is rare.


Customer: replied 7 years ago.
Which one is more effective for lowering your blood pressure? I have been told that to stop taking Coreg CR that the dosage should be lowered and a lower dosage should be taken for one week before starting any other blood pressure medicine. Also that stop taking Coreg can cause heart failure! Since they work in different ways Is there any side effect to going from Coreg CR to Diovan? Thanks

They are about equally effective at treating high blood pressure. Coreg is also used to treat heart failure, so stopping Coreg may uncover heart failure that is being treated, but stopping Coreg will not cause heart failure if it was not already present. All blood pressure medicines should be tapered if on a higher dose and tapering over a week is reasonable. When it is best to start the new medicine depends upon what your blood pressure is running. There is no intrinsic risk to changing to a different mechanism, although there are the possible side effects to the new medicine.


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