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Dr. Abby
Dr. Abby, US Board Certified MD
Category: Medical
Satisfied Customers: 10330
Experience:  Family Physician practicing medicine for over 10 years, United States
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What is the difference between depomedrol and solumedrol?

Resolved Question:

what is the difference between depomedrol and solumedrol?
Submitted: 8 years ago.
Category: Medical
Expert:  Dr. Abby replied 8 years ago.
Depo-Medrol and Solu-Medrol are both methylprednisolone, which is the same medication.

Depo-Medrol is a suspension (liquid formulation) and Solu-medrol is a powder that needs to be reconstituded in to a liquid before injection.

Depo-medrol is methylprednisolone acetate and Solu-medrol is methylprednisolone sodium succinate.
Different formulations of the same drug.
Only Solu-medrol form can be given IV.
I hope that answers your question. If you have more questions, let me know.

Dr Abby
Customer: replied 8 years ago.
if it is used for tendon injections, is one more effective than the other?
Expert:  Dr. Abby replied 8 years ago.
Depo-Medrol is a longer acting injection, so that would be used for a tendon injection.
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Customer: replied 8 years ago.

THANK YOU! I have been looking for this answer for weeks. I have asked RNs and MDs. You're the best!