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Dr. B.
Dr. B., Veterinarian
Category: Large Animal Veterinary
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Experience:  As a veterinarian, I have been educated to treat all animals, big and small.
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Is it possible that a Positive test could be caused by a

Customer Question

Is it possible that a Positive test for PI could be caused by a modified live virus vaccination?
Submitted: 1 year ago.
Category: Large Animal Veterinary
Expert:  Dr. B. replied 1 year ago.

Hello and welcome. I am Dr. B, a licensed veterinarian and would like to help you today.

In regards ***** ***** question, the potential effects of the modified live vaccination on testing depends on when she was vaccinated and what test was actually done. If the heifer was tested within 3 weeks after vaccination using a test that checked for antibodies or immunohistochemistry (IHC), then it is possible to get a vaccine induced false positive and a confirmation test (ie an Antigen-ELISA, PCR, virus isolation, etc) should be checked once that >3 weeks post vaccination period has passed to make sure that test result is valid. Of course, in the meantime, the heifer should be isolated and barrier nursed to reduce any risk to the herd until the confirmation results are available.

I hope this information is helpful.

If you need any additional information, do not hesitate to ask!

All the best,

Dr. B.


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