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Ask Dr. Muneeb Ali Your Own Question
Dr. Muneeb Ali
Dr. Muneeb Ali, Doctor
Category: HIV and AIDS
Satisfied Customers: 6718
Experience:  MBBS, MD, MCCM. Currently working in Critical Care Medicine with 10 year experience in Medicine
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Accurate is a 5th generation hiv blood test sent to the lab

Customer Question

Hi accurate is a 5th generation hiv blood test sent to the lab at 8 weeks after low risk exposure?
JA: In general, how has your health been lately?
Customer: Fine
JA: Anything else in your medical history you think the doctor should know?
Customer: No
Submitted: 3 months ago.
Category: HIV and AIDS
Expert:  Dr. Muneeb Ali replied 3 months ago.

Hi,

Welcome to JA and thanks for this question. Actually the 5th generation assay is a relatively newer test and the only difference between it and the 4th generation one is that it is able to detect antibodies against HIV 1 and HIV 2 in addition to the antigen. So it is a test which has a GREATER accuracy in detecting HIV as compared to the 4th generation test. Now coming to its accuracy at 8 weeks post exposure, actually at this point after the exposure it has a VERY HIGH accuracy in detecting HIV. The test can detect upto 98-99% of all HIV infections at 8 weeks. So the simple answer here would be that it is VERY accurate at 8 weeks. In order to achieve the maximum accuracy you would need to be tested at 12 weeks which yields an accuracy of 99.9%. However it is uncommon that a person who tests negative at 8 weeks would test as positive at 12 weeks. Usually those who test negative at 8 weeks would also test as negative at 12 weeks.

But to answer your question, the 5th generation test is very accurate at 8 weeks detecting 98% of HIV infections.

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