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Ask Dr. Arun Phophalia Your Own Question
Dr. Arun Phophalia
Dr. Arun Phophalia, Doctor (MD)
Category: Health
Satisfied Customers: 35032
Experience:  MBBS, MS (General Surgery), Fellowship in Sports Medicine
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I have recently been diagnosed with Auto Immune Hepatitis.

Customer Question

I have recently been diagnosed with Auto Immune Hepatitis. My doctor has me getting regular blood tests and I'm currently on 30 mg of Prednisone. They are not good about communicating the results or how I should be adjusting my meds. I'm to be going onto a new med this evening, Budesonide, 3 mg and I'm to take it 3 X day.
JA: OK. The Doctor will need to help you with this. Is there anything else the Doctor should be aware of?
Customer: I'm not getting call backs from my current specialist. So i finally got them to fax me my blood results from last Saturday. I have a few that are high and one that is low. My problem is I'm not sure what all these stand for or if I should be seriously concerned. i have diabetis in my family, father, daughter, granddaughter so I'm well versed on Diabetes, nowever I've always been fine until the Prednesone which i understand can cause levels to go up. The ones I'm concerned about is WBC 13.9, MCH 31.9, RDW 18.5, Absolute Neutrophils 9.7, Globulin 4.5, AST 91 (was over 1400 when i was admitted 4 weeks ago. and ALT 170 (was over 1600 when admitted4 weeks ago) I was admitted for 4 days, off 2 weeks and I've been back to work since 4/11. The prednesone is playing havoc with my system so I'm very anxious to get off of it. Just ready to find a new specialist. Communication is less than acceptable.
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Submitted: 1 year ago.
Category: Health
Expert:  Dr. Arun Phophalia replied 1 year ago.


I am Dr. Arun and will be helping you today.

I am sorry that your question was unanswered for long.

These investigations (WBC 13.9, MCH 31.9, RDW 18.5, Absolute Neutrophils 9.7) are usually deranged mildly in an inflammation and autoimmune disorder. None of these are alarming presently. A mild high WBC and absolute neutrophils denote mild grade infection or inflammation which can change the mean corpuscular hemoglobin (MCH) and RDW of the red blood cells.

The globulin, AST and ALT are liver function tests. They would derange in autoimmune hepatitis but presently are far better than when you were admitted so you are responding to the treatment. You may need to continue steroids for some more duration in the same dose till all the investigations comes back to normal.

Please feel free for your follow up questions.

I would be happy to assist you further, if you need any more information.

Thanks for using Just Answer.

Customer: replied 1 year ago.
Thank you for your prompt response. Have you seen these levels return to this level before and do you feel this may be just a temporary issue and that there is a POSSIBILITY that I may not need these steroids in the future?
Expert:  Dr. Arun Phophalia replied 1 year ago.

You are very welcome.

There are some patients (about 30-40%), who may not need steroids at all later on . Unfortunately some will require off and on steroids as liver enzymes may dwindle in future. They are likely to return to normal and stay normal for long duration in whom autoimmune hepatitis is mild.

It is privilege assisting you.

Please let me know if you have further queries or unanswered questions.

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Thank you.

Wishing you all the very best in life.

Expert:  Dr. Arun Phophalia replied 1 year ago.

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Expert:  Dr. Arun Phophalia replied 1 year ago.

Best wishes,
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