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nootropic formulas are not directly harmful
but as with all herbal products, both their efficacy and their side effects are not known
though herbal products are generally expected to be safe
yet many are known to be toxic sometimes
nootropic formulas in general are not known to cause neurotoxic effects
but some herbal products, though not the ones used in such formulas, are known to cause harm to the liver and kidneys
but this is generalized for all herbal products in general
nootropic formulas are not more harmful than other herbal products nor are they known to cause any neurotoxicity
i believe they are just combining so as to make their formulas more attractive
since nootropic formulas are quite the rage now
otherwise the two are not connected to each other
you can go ahead and have such supplements
but if you are taking any prescription medicines, you should discuss with your doctor first before taking any herbal medicines
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glad to help