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Ask Dr. Arun Phophalia Your Own Question
Dr. Arun Phophalia
Dr. Arun Phophalia, Doctor (MD)
Category: Health
Satisfied Customers: 35027
Experience:  MBBS, MS (General Surgery), Fellowship in Sports Medicine
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I have been searching for answers to an infection in my foot

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I have been searching for answers to an infection in my foot for some time now. About a year ago I had several mesquite thorns lodge in my shoe so I pulled them out and kept on going not knowing they were poisonous and totally forgot about the incident. About a month later I had an itch on the bottom of my foot and did not associate the wound with the incident with the thorns. I treated for athlete's foot even though I have never had this problem in my life. Many health issues have since developed and the foot has mushroomed out of control with watery blisters, uncontrollable itching along with blistering on both hands. I have been to several doctors that are completely stumped. I finally spent much time in meditation and the incident of the mesquite thorns just keeps returning to me as that is the only thing it could be. Since it has been nearly a year since this happened the doctors are leery of my story. I have soaked in Epsom salts, dome burro, used peroxide, arnica gel and pellets as well as Benadryl and Benadryl cream, fluocinodid ointment and others. Is there an oral antidote for this poison? And what can I do to calm the itch and dry the blisters? Any information would be most welcome.
Hello Mari-Ann,

I am sorry that your question was unanswered for long.

Were any blood work or culture tests done?
Are you diabetic?

Dr. Arun
Customer: replied 4 years ago.

No blood work was done and no culture tests and I am not diabetic.


Hello Mari-Ann,

The culture tests are the key to diagnose the issue. A bacterial culture, culture for mycobacterium and a fungal culture are necessary for the diagnosis. The culture test also gives the right therapeutic protocol, which will be able to treat the issue. You need to consult an infectious disease specialist. The mosquito bite may or may not be related, which occasionally cause viral infection or autoimmune disease (which is responsible for the blisters). A blood work for the autoimmune panel is also advised for the diagnostic clues.

Please feel free for your follow up questions.

I would be happy to assist you further, if you need any more information.

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Customer: replied 4 years ago.

I believe you misread mesquite thorns (tree) for mosquito. My question is - is there any antidote for mesquite poisoning?

Thank you,


Mari Ann,

I am extremely sorry for misreading and misunderstanding the question.

Your symptoms are suggestive of plant thorn synovitis which is a known autoimmune / inflammatory disorder. The foot blisters can be caused by it. An MRI and following blood work should be able to clinch the diagnosis;

1) ANA
2) RA factor
3) CRP
4) Anti dS DNA

You would need medications called as immune modulators. Please read about plant thorn synovitis;

It is privilege assisting you.

Dr. Arun
Dr. Arun Phophalia and other Health Specialists are ready to help you
Customer: replied 4 years ago.

Thank you Doctor. Women get tired of doctors telling them it's all in their head and they really don't believe us when we try to explain what happened. I am well satisfied with your answer. Now I know I'm not crazy and I know what to do to heal my entire body.

Thanking you again I remain.

Mari-Ann Alston


You are very welcome, Mari-Ann Alston.

It is privilege assisting you.

Please feel free for your follow up queries.