Health

Ask Health Experts and Get Answers to Your Health Question ASAP

Ask an Expert,
Get an Answer ASAP!

Health
This answer was rated:

I am having a workup done for Hereditary Angioedema. My

Compliment CH50 Came back elevated...
I am having a workup done for Hereditary Angioedema. My Compliment CH50 Came back elevated at 65 with the refereence range 22-60.. All the other results were in normal range C1,2,3... I was medicated at the time of these tests. Does this mean I do not have the disease?
Show More
Show Less
Ask Your Own Health Question
Answered in 6 minutes by:
3/22/2013
Onlinedoc
Onlinedoc, General Physician
Category: Health
Satisfied Customers: 3,131
Experience: General physician with experience in General & Family Medicine,Ayurveda, Integrative, CAM
Verified

Hi,

Have you undergone other blood work like CBC,ESR,IgM,CRP,IgE?

What are your current symptoms?

Ask Your Own Health Question
Customer reply replied 4 years ago

Yes, all within normal range.

My current symptoms consist of systemic hives, and angioedema of the face.

I am under the impression the dx of this disease is very complex and often over looked.

Hi,
Thanks for providing more information.

A high count on the CH50 test means that your total complement system (part of the immune system) is hyperactive that goes along with an overactive immune disease and increased in infection.

Typically, other tests that are more specific for the suspected disease are performed first. C3 and C4 are the most commonly measured complement components.

And as C3 and C4 are normal in your case so slightly raised CH50 is not significant.

However usually low levels of CH50 are seen in Hereditary angioedema.

The increase or decrease in the complement levels assessed by the Complement CH50 test is not always an accurate indicator of what the exact problem is.

However, this test enables a doctor to determine if the immune system is involved with the ailment in any way.

So further a clinical corelation is required in your case.

I suggest you to consult your doctor as well.

Hope this helps.
Please rate me high if you are satisfied with our conversation.
In case you have further query press reply to expert button.
Bonus and positive feedback are appreciated.
Thanks.

Onlinedoc
Onlinedoc, General Physician
Category: Health
Satisfied Customers: 3,131
Experience: General physician with experience in General & Family Medicine,Ayurveda, Integrative, CAM
Verified
Onlinedoc and 87 other Health Specialists are ready to help you
Ask your own question now
Customer reply replied 4 years ago

Does this mean it is strictly an allergy?

Hi,

Sorry for late reply and inconvenience.

High CH50 levels itself doesn't indicate allergy.

However as per your description and current symptoms,allergy can be a possible cause.

So discuss it with your doctor as well.

I hope this helps.

Ask Your Own Health Question
Ask Onlinedoc Your Own Question
Onlinedoc
Onlinedoc
Onlinedoc, General Physician
Category: Health
Satisfied Customers: 3,131
3,131 Satisfied Customers
Experience: General physician with experience in General & Family Medicine,Ayurveda, Integrative, CAM

Onlinedoc is online now

A new question is answered every 9 seconds

How JustAnswer works:

  • Ask an ExpertExperts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional AnswerVia email, text message, or notification as you wait on our site. Ask follow up questions if you need to.
  • 100% Satisfaction GuaranteeRate the answer you receive.

JustAnswer in the News:

Ask-a-doc Web sites: If you've got a quick question, you can try to get an answer from sites that say they have various specialists on hand to give quick answers... Justanswer.com.
JustAnswer.com...has seen a spike since October in legal questions from readers about layoffs, unemployment and severance.
Web sites like justanswer.com/legal
...leave nothing to chance.
Traffic on JustAnswer rose 14 percent...and had nearly 400,000 page views in 30 days...inquiries related to stress, high blood pressure, drinking and heart pain jumped 33 percent.
Tory Johnson, GMA Workplace Contributor, discusses work-from-home jobs, such as JustAnswer in which verified Experts answer people’s questions.
I will tell you that...the things you have to go through to be an Expert are quite rigorous.

What Customers are Saying:

I can go as far as to say it could have resulted in saving my sons life and our entire family now knows what bipolar is and how to assist and understand my most wonderful son, brother and friend to all who loves him dearly. Thank you very much

Corrie MollPretoria, South Africa

I thank-you so much! It really helped to have this information and confirmation. We will watch her carefully and get her in for the examination and US right away if things do not improve. God bless you as well!

ClaudiaAlbuquerque, NM

Outstanding response time less than 6 minutes. Answered the question professionally and with a great deal of compassion.

KevinBeaverton, OR

Suggested diagnosis was what I hoped and will take this info to my doctor's appointment next week.
I feel better already! Thank you.

ElanorTracy, CA

Thank you to the Physician who answered my question today. The answer was far more informative than what I got from the Physicians I saw in person for my problem.

JulieLockesburg, AR

You have been more help than you know. I seriously don't know what my sisters situation would be today if you had not gone above and beyond just answering my questions.

John and StefanieTucson, AZ

I have been dealing with an extremely serious health crisis for over three years, and one your physicians asked me more questions, gave me more answers and encouragement than a dozen different doctors who have been treating me!!

Janet VPhoenix, AZ

< Previous | Next >

Meet the Experts:

Family Physician

Family Physician

Doctor (MD)

5,660 satisfied customers

Emergency Medicine and Family Practice for over 26 years

Nurse Milli, RN

Nurse Milli, RN

Nurse (RN)

4,051 satisfied customers

20 years experience in many areas of Nursing. Both Hospital and Private Practice experience.

Dr. Ketch

Dr. Ketch

Doctor

102 satisfied customers

Medical Degree, Former Assistant Professor at School of Medicine at Yale University

DrRussMD

DrRussMD

Doctor (MD)

5,095 satisfied customers

Practice Director

Dr. Arun Phophalia

Dr. Arun Phophalia

Doctor (MD)

19,749 satisfied customers

MBBS, MS (General Surgery), Fellowship in Sports Medicine

Dr. Chip

Dr. Chip

Doctor (MD)

14,036 satisfied customers

Over 20 yrs of Family Practice

Dr. Mark

Dr. Mark

Doctor (MD)

6,234 satisfied customers

U.S. Physician/Surgeon in Neurosurgery

< Previous | Next >

Related Health Questions
I was bitten by a cat yesterday. I am taking Augmentin and a
I was bitten by a cat yesterday. I am taking Augmentin and a Medrol Dose pack, which I started yesterday. I was also given Percocet for pain. I take Klonopin 2mg every night. I took Percocet at 6 PM a… read more
Onlinedoc
Onlinedoc
General Physician
3,131 satisfied customers
Arun A while back I pulled my hamstring (muscle behind the
Hello doctor Arun A while back I pulled my hamstring (muscle behind the knee, bellow knee) so I started wearing brace all summer long in a day time only of course, I do not wear it any longer as of 4 … read more
Dr. Arun Phophalia
Dr. Arun Phophalia
Doctor (MD)
Post-Doctoral Degree
19,749 satisfied customers
I was preparing macaroni salad and had all the ingredients
Hi. I was preparing macaroni salad and had all the ingredients on my table. I left for literally 20 seconds max to check my phone. When I got back to the kitchen, my cat was nibbling on a portion of t… read more
Dr. Kara
Dr. Kara
Doctoral Degree
5,383 satisfied customers
1) Is it healthy to eat grilled chicken when it's grilled
Hello,1) Is it healthy to eat grilled chicken when it's grilled with charcoal? Some people say it's not healthy.2) In general, what's the healthiest option to prepare chicken?… read more
Dr. Scott
Dr. Scott
Doctor
1,026 satisfied customers
I had unprotected oral sex with a man I do not know well. He
Hello. I had unprotected oral sex with a man I do not know well. He assured me that he was negative for STD' s and that he gets tested regularly. He came in my mouth a little bit but I pulled away and… read more
Dr. Arun Phophalia
Dr. Arun Phophalia
Doctor (MD)
Post-Doctoral Degree
19,749 satisfied customers
I'm not having bowel movements and I don't feel hungry, but
I'm not having bowel movements and I don't feel hungry , but I eat anyway. … read more
Dr Ted Manos
Dr Ted Manos
Self Employed
MD
796 satisfied customers
I was prescribed Prednisone for an upper respiratory
I was prescribed Prednisone for an upper respiratory infection. I took 40 mg yesterday and 20 today. I cannot stand the side effects. Can I stop taking it after 2 days ? I did cut the dose in half tod… read more
Dr. Scott
Dr. Scott
Doctor
1,026 satisfied customers
My 14 year old son has been sick since, 11/10/17. He had
My 14 year old son has been sick since, 11/10/17. He had random fevers and sore throat and ear aches and overall not feeling well. On 12/6/17, he was diagnosed the first time with strep and put on a 7 day course of antibiotics. When I saw that he was still not feeling well, I took him back to the family doctor who on 12/15/17 diagnosed him with strep again and placed him on a 10 day course ion Penicillin. … read more
Dr. Muneeb Ali
Dr. Muneeb Ali
Senior Registrar Critical Care Medicine
Doctoral Degree
7,277 satisfied customers
My blood test came back Imm grand, Not sure, Had diarrhoea
My blood test came back Imm grand JA: Is this a time sensitive issue? What type of specimen are they testing? Customer: Not sure JA: Anything else in your medical history you think the doctor should k… read more
Dr. Arun Phophalia
Dr. Arun Phophalia
Doctor (MD)
Post-Doctoral Degree
19,749 satisfied customers
My creatinine level is 1.4 and my bun creatinine is 35.
My creatinine level is 1.4 and my bun creatinine is 35. I'm In advanced Addison Disease. My liver is severe NAFLD, damage to the left side of my heart, gastreoperisis, and now my kidneys in just one y… read more
Dr Ted Manos
Dr Ted Manos
Self Employed
MD
796 satisfied customers
Please help me, No i just took the oraquick hiv test and
No i just took the oraquick hiv test and tested negative but I drank a few sips of iced tea and directions say no eating or drinking within 30 minutes of taking the test I'm crying and losing my mind . The test checks the antibodies in the saliva do u know if this test is not accurate because I drank 15 before … read more
Onlinedoc
Onlinedoc
General Physician
3,131 satisfied customers
I had hcg blood test stating <2mIU. What does that mean.
hi JA: Hello. How can I help? Customer: I had hcg blood test stating <2mIU JA: Is this a time sensitive issue? What type of specimen are they testing? Customer: what does that mean JA: Anything els… read more
Dr. Muneeb Ali
Dr. Muneeb Ali
Senior Registrar Critical Care Medicine
Doctoral Degree
7,277 satisfied customers
I have a question about Xanax. I took .25 mg of Xanax at
I took .25 mg of Xanax at bedtime only for about 2 years. I stopped taking it at night about 2 weeks ago & now I am experiencing insomnia. Maybe sleeping 2 hours at the most. Could the insomnia be a result of stopping the Xanax even though I took such a low dose? I did/do not take it any other time. … read more
Dr. Rahman
Dr. Rahman
Fellow Physician in Child Neurology
Doctorate of Medicine
4 satisfied customers
I asked a new question because you were helpful and being
I asked a new question because you were helpful and being honest. I forgot to ask .. if I had Postive IgM 39,23,41. And I had IGg 18,66,41. Being that the 39 and 23 we're Postive. Do they automaticall… read more
Dr Ted Manos
Dr Ted Manos
Self Employed
MD
796 satisfied customers
Doc new question about something that freaked me out. About
Ok doc new question about something that freaked me out. About 5 min ago I was sitting in my car looking down at my phone and the light turned free I looked up and got dizzy, like dizzy SITTING... as … read more
Dr. Chip
Dr. Chip
Doctor (MD)
M.D.
14,036 satisfied customers
I was having sex with my girlfriend and tore my frenulum.
I was having sex with my girlfriend and tore my frenulum … read more
Dr. Muneeb Ali
Dr. Muneeb Ali
Senior Registrar Critical Care Medicine
Doctoral Degree
7,277 satisfied customers
Had a question about the flu. I've been reading about people
Hey I had a question about the flu. I've been reading about people getting vaccinated and not only are getting sick but dying from flu complications, especially children. This has me concerned. My dau… read more
Dr. Chip
Dr. Chip
Doctor (MD)
M.D.
14,036 satisfied customers
I have a similar question to this post. Last night I was
Hi yes I have a similar question to this post. Last night I was throwing up and yelling ( I know sounds weird ) but after I threw up, I was gagging and immediately I felt pain on the right side of my … read more
Onlinedoc
Onlinedoc
General Physician
3,131 satisfied customers
Disclaimer: Information in questions, answers, and other posts on this site ("Posts") comes from individual users, not JustAnswer; JustAnswer is not responsible for Posts. Posts are for general information, are not intended to substitute for informed professional advice (medical, legal, veterinary, financial, etc.), or to establish a professional-client relationship. The site and services are provided "as is" with no warranty or representations by JustAnswer regarding the qualifications of Experts. To see what credentials have been verified by a third-party service, please click on the "Verified" symbol in some Experts' profiles. JustAnswer is not intended or designed for EMERGENCY questions which should be directed immediately by telephone or in-person to qualified professionals.

Disclaimer: Information in questions, answers, and other posts on this site ("Posts") comes from individual users, not JustAnswer; JustAnswer is not responsible for Posts. Posts are for general information, are not intended to substitute for informed professional advice (medical, legal, veterinary, financial, etc.), or to establish a professional-client relationship. The site and services are provided "as is" with no warranty or representations by JustAnswer regarding the qualifications of Experts. To see what credentials have been verified by a third-party service, please click on the "Verified" symbol in some Experts' profiles. JustAnswer is not intended or designed for EMERGENCY questions which should be directed immediately by telephone or in-person to qualified professionals.

Show MoreShow Less

Ask Your Question

x