Following can be the causes of pain in the leg;
1) Tight muscles; need stretching exercises.
2) An underactive thyroid gland
3) Thiamine deficiency
4) Vitamin B 12 deficiency (pernicious anemia)
5) Vitamin B 6 (pyridoxine) taken in excessive amounts
6) Drugs, medications, herbs.
8) Pinched nerves in back and neck
9) Peripheral arterial disease.
You should get the following investigations done (if not yet done);
1) Electromyography/nerve conduction studies (EMG/NCS)
2) MRI of the spine and brain
3) blood glucose and glycosylated hemoglobin
4) serum B12 level with methylmalonic acid (with or without homocysteine),
5) serum protein electrophoresis
6) Anti-nuclear antibody
7) Lyme testing
8) Rheumatoid factor
9) Sjogren's syndrome testing (Anti-Ro, Anti-La Antibodies)
10) Muscle enzymes
11) Thyroid, parathyroid and adrenal hormone assay.
These should be able to clinch the diagnosis of muscle pain leg pain.
Please feel free for your follow up questions.
I would be happy to assist you further, if you need any more information.
We have recently implemented a new rating and feedback system. Please be aware that you are rating my courtesy and service as a professional. If you have any questions whatsoever, or there is anything I can clarify for you, please temporarily bypass the rating system by clicking “Continue the Conversation” or "Reply."
Clicking either of the lowest two options reflects poorly on me so please reply to me if there is anything else I can do to help before choosing those options. I appreciate your patience while we work out the kinks. It's important to me that you are 100% satisfied with the service I have provided you. Thank you.